Myxoid variant of adrenocortical carcinoma in a middle aged female - A case report


Case Report

Author Details : Naba Hasan, Fatima Meraj, Suhailur Rahman, Kafil Akhtar*

Volume : 6, Issue : 1, Year : 2021

Article Page : 76-79

https://doi.org/10.18231/j.jdpo.2021.017



Suggest article by email

Get Permission

Abstract

Adrenocortical neoplasms are rare tumours that can be diagnostically challenging in some cases. Numerous diagnostic algorithms and scoring systems are in practice to differentiate adenoma from carcinoma. Besides, the different histological variants of adrenocortical carcinoma need to be identified. We present a case of 44 year old female with vaginal bleeding with a large, heterogenous suprarenal mass on imaging. Provisional clinical diagnosis of pheochromocytoma was made and patient underwent adrenalectomy. The histological examination of tumour sections showed sheets and trabeculae of moderately pleomorphic cells
with extracellular mucin deposition. Immunohistochemical evaluation showed tumour cells to be negative for chromogranin with focal pan cytokeratin positivity. Finally a diagnosis of adrenal cortical carcinoma – myxoid variant was made. Post operative period was uneventful and following en bloc resection of the tumour patient did not receive any adjuvant adrenolytic treatment. The patient is doing well at 6 months of follow up period, without any evidence of recurrence.

Keywords: Adrenal cortical malignancy, Cytokeratin, Histopathology, Immunohistochemistry, Myxoid.


How to cite : Hasan N , Meraj F , Rahman S , Akhtar K , Myxoid variant of adrenocortical carcinoma in a middle aged female - A case report. IP J Diagn Pathol Oncol 2021;6(1):76-79


This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.







Article History

Received : 16-12-2020

Accepted : 22-01-2021


View Article

PDF File   Full Text Article


Copyright permission

Get article permission for commercial use

Downlaod

PDF File   XML File   ePub File


Digital Object Identifier (DOI)

Article DOI

https://doi.org/10.18231/j.jdpo.2021.017


Article Metrics






Article Access statistics

Viewed: 933

PDF Downloaded: 563



Medical Abbreviation List