To correlate the value of neutrophil to lymphocyte ratio with prognosis of ST-elevation myocardial infarction and non ST-elevation myocardial infarction patients at a tertiary care hospital

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Original Article

Author Details : Muralidhar Bhat Y, Arpitha V*, Shreya M Bhat, Shivakumar S

Volume : 5, Issue : 2, Year : 2020

Article Page : 135-140

https://doi.org/10.18231/j.jdpo.2020.028

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Abstract

Introduction : Myocardial infarction (MI) is one of the leading causes of death in India. Atherosclerosis is
the major predisposing factor. Leucocytes play an important role in the formation of arterial thrombus, the
healing process and the reperfusion injury in post-MI cases. Hence Neutrophil to Lymphocyte Ratio [NLR]
is a potential marker to determine inflammation in cardiac disorders. It is inexpensive, easy to obtain and is
widely available.
Material and Methods: A detailed medical history was obtained from the study population. Report of
ECG changes, absolute neutrophil count and absolute lymphocyte count at the time of admission was
noted down from the laboratory reports attached to the case sheets. The NLR was calculated.
The patients were classified into 2 groups based on ECG changes
1. STEMI group
2. NSTEMI group
Follow up was done for the duration of hospitalisation and complications, if any during this period were
noted.
Discussion: The study included a total of 62 study subjects with 31 in STEMI group and 31in NSTEMI
group. Among MI cases with NLR < 2> Among MI cases with NLR 2.5, 13/47 cases were referred to higher centre and 34/47 were discharged. In
this study, NLR between 2 groups had no statistically significant difference in occurrence of complications
Conclusion: This study demonstrated that average NLR is not useful indicator of adverse-outcomes during
hospitalization in patients presenting with STEMI and NSTEMI.

Keywords: Myocardial infarction, STEMI, NSTEMI, Neutrophil to Lymphocyte ratio.

How to cite : Muralidhar Bhat Y, Arpitha V, Bhat S M, Shivakumar S, To correlate the value of neutrophil to lymphocyte ratio with prognosis of ST-elevation myocardial infarction and non ST-elevation myocardial infarction patients at a tertiary care hospital. IP J Diagn Pathol Oncol 2020;5(2):135-140

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