Indian Journal of Pharmacy and Pharmacology

Print ISSN: 2393-9079

Online ISSN: 2393-9087

CODEN : IJPPTK

Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award programs. With more...

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Original Article


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161-167


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Roshan S*, Syed Mamoon Hussain


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Anti stress activity of olea europaea


Original Article

Author Details : Roshan S*, Syed Mamoon Hussain

Volume : 8, Issue : 2, Year : 2021

Article Page : 161-167

https://doi.org/10.18231/j.ijpp.2021.026



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Abstract

Stress and stressor-related disorders are the global illnesses. The immune system isthought to be strengthened by apoptogenic substances due to their ability of restoring normal body functions, which were imbalanced due to the presence of stressful conditions. The aim of study is to evaluate anti stress potential in ethanolic extract of Olea europaea (O. europaea) leaves on swimming endurance test in mice, cold and immobilization stress in rats. The effect was assessed by swimming survival time and estimation of biochemical parameter, weight of gland, organs, blood count in cold and immobilization stress at a dose 400 and 600 mg/kg per oral(p.o). The results demonstrated on comparison with stress models with O. europaea leaf extract and Gerifort Syrup showing significant increase (p<0> It was experimentally compared to control and gerifort group. Thus, obtained results revealed that the leaf extract of O. europaea have potential Anti-stress activity due to the existence of phenolic compounds, especially secoiridoids and iridoids and antioxidant molecules, such as oleuropein, hydroxytyrosol, tyrosol, caffeic acid, and ligstroside proving its significant anti stress activity.

Keywords: Swimming, Cold stress, Olea europaea, WBC, BUN, TG.


How to cite : Roshan S, Hussain S M, Anti stress activity of olea europaea. Indian J Pharm Pharmacol 2021;8(2):161-167

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