Indian Journal of Pharmacy and Pharmacology

Print ISSN: 2393-9079

Online ISSN: 2393-9087

CODEN : IJPPTK

Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award programs. With more...

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Original Article


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130-135


Authors Details

Ahmed Abdul Bari Hazari*


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Efficacy of tiotropium bromide inhalation in COPD and bronchial asthma patients for a period of 14 weeks


Original Article

Author Details : Ahmed Abdul Bari Hazari*

Volume : 7, Issue : 2, Year : 2020

Article Page : 130-135

https://doi.org/10.18231/j.ijpp.2020.022



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Abstract

Background: Chronic Obstructive Pulmonary Disease affects more than 15 million Americans, with the
majority of the patients more than 50 years old with current or past smokers.
Objective: To study the safety and efficacy of Tiotropium bromide inhalation in both COPD & Bronchial
Asthma patients.
Materials and Methods: The present study was conducted in patients with stable as well as exacerbated
COPD and Br. Asthma at Shadan Hospital, Telangana.
Results: Significant improvement in Forced expiratory volume with respect to baseline at the end of the
14th week. The maximum mean response in FEV1 improved by 0.221, (68.03%) when the compared value
of baseline 0.13L (p-value < 0> compared to COPD treatment group. The Forced expiratory volume (FEV1), Forced vital capacity (FVC)
and FEV1/FVC ratio were improved with respect to baseline.
Conclusion: Tiotropium via dry powder inhaler result in 24 hr bronchodilation as well as consistent and
sustained improvement for both the COPD and the Bronchial Asthma patients.

Keywords: Bronchial asthma, COPD, FEV1, FVC, FEV1/FVC ratio.


How to cite : Hazari A A B, Efficacy of tiotropium bromide inhalation in COPD and bronchial asthma patients for a period of 14 weeks. Indian J Pharm Pharmacol 2020;7(2):130-135

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