---

Design of chemical synthesis of trioxan derivatives in respect of artemisinin as anti malarial drug

Full Text PDF Share on Facebook Share on Twitter

---

Original Article

Author Details : Gautam Girendra Kumar*

Volume : 9, Issue : 1, Year : 2022

Article Page : 22-27

https://doi.org/10.18231/j.ijpca.2022.004

Suggest article by email

Get Permission

Abstract

Trioxane is a six membered heterocyclic ring system with Carbon, Hydrogen and Oxygen where the oxygen is hetero atoms. Trioxane has total three oxygen atom in its ring. It can be the alternate of Artemisinin that shows anti malarial activity. Substituting trioxane can be prepared by various substitutions perhaps in the minimum requirement to show biological activities similar to Artemisinin. Artemisinin is a Chinese herb that has been used in the treatment of fevers for over 1,000 years. The chemical composision of Artemisinin is known and structurally it also has heterocyclic ring comprising the oxygen. So, Author proposed the findings of possibility of synthesis of trioxane in respect of Artemisinin as trioxane derivatives through different complex pathways. This paper focus on different strategies followed for the convenient synthesis of trioxane derivatives.

Keywords: Trioxane, Artemisinin, Design, Chemical Synthesis, Anti malarial, Strategies

How to cite : Kumar G G, Design of chemical synthesis of trioxan derivatives in respect of artemisinin as anti malarial drug. Int J Pharm Chem Anal 2022;9(1):22-27

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.