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Chemistry and activity of quinazoline moiety: A systematic review study

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Original Article

Author Details : Jagmohan Singh Negi, Ajay Singh Bisht*, D K Sharma

Volume : 7, Issue : 2, Year : 2020

Article Page : 61-65

https://doi.org/10.18231/j.ijpca.2020.009

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Abstract

Quinazoline is a compound with amalgamated heterocyclic system popular for their biological activities.
Quinazoline is a compound made up six membered fused aromatic rings i,e a benzene ring with pyrimidine
ring. Its chemical formula is C8H6N2O. It is yellow colour and found in the crystalline form. Molecular
optimization of potentially lead compounds through a chemist is an needy and upcomming approach for the
discovery of new pharmaceuticals. More than two combinations of pharmacophore and making them one
moiety is a noval and popular procedure of exploitation of synthesis now a days and this cause an additive
increment of biological activities with taking away of surplus side effects. Present communication studies
about the structure origin, diversity and chemical modification with change in pharmacological activities
of Quinazoline.

Keywords: Quinazoline, Molecular modification, Pharmaceuticals, Pharmacological activity.

How to cite : Negi J S , Bisht A S , Sharma D K , Chemistry and activity of quinazoline moiety: A systematic review study. Int J Pharm Chem Anal 2020;7(2):61-65

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