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Increased first trimester serum uric acid as a predictor of Gestational diabetes mellitus

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Original Article

Author Details : Irkm Sivasarupa, Ushadevi Gopalan*, Sivankumar Kumarapillai

Volume : 8, Issue : 3, Year : 2021

Article Page : 292-295

https://doi.org/10.18231/j.ijogr.2021.063

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Abstract

Introduction: Women with raised uric acid in pregnancy are interlinked with more incidence of unfavourable outcomes in pregnancy such as gestational diabetes mellitus. The study aims at testing the hypothesis that elevated uric acid in first trimester of pregnancy is associated with subsequent development of gestational diabetes.
Materials and Methods: All pregnant women less than 12 weeks were included in this study after informed consent. Blood samples were collected for serum uric acid analysis and all these patients were followed up with oral glucose tolerance test at twenty-four to twenty-eight weeks of gestation.
Results: The mean age of pregnant women was 29.84 ± 4.94 years. The mean height and weight was 151.52 ± 7.49 cms and 50.60 ± 6.88 kg respectively. The body mass index of patients was 22.13 ± 3.31 kg/m.The mean gestational age of pregnant women was 11.14 ± 1.30 weeks. The mean uric acid level was 3.81 ± 1.24 mg/dl. In this study the p value was 0.018 using chi-square test which was significant.
Conclusion: Hyperuricemia in first trimester is a reliable marker for the prediction of gestational diabetes mellitus in later pregnancy.
 

Keywords: Gestational diabetes mellitus, Serum uric acid, Oral glucose tolerance test, First trimester.

How to cite : Sivasarupa I, Gopalan U, Kumarapillai S, Increased first trimester serum uric acid as a predictor of Gestational diabetes mellitus. Indian J Obstet Gynecol Res 2021;8(3):292-295

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