Relationship of Serum Vitamin D levels with Nerve Conduction Velocity in patients of Diabetic Neuropathy


Original Article

Author Details : Saquib Alam, Kafil Akhtar*, Syed A Abbas, Sheelu S Siddiqui, Shagufta Moin

Volume : 6, Issue : 2, Year : 2020

Article Page : 96-100

https://doi.org/10.18231/j.ijn.2020.020



Suggest article by email

Get Permission

Abstract

Introduction: Although vitamin D insufficiency is very prevalent in Type-2 diabetes mellitus, there are no studies to prove its role or association in diabetic peripheral neuropathy.
Aims and Objectives: We intend to highlight the relationship of Serum Vitamin D levels with Nerve Conduction Velocity in patients of Diabetic Peripheral Neuropathy.
Material and Methods: 52 patients of diabetic neuropathy were assessed for sensory and motor nerve conduction velocity along with serum Vitamin D levels estimation and the results were statistically
analyzed.
Results: Tingling was the most common symptom, seen in 31.1% cases. The numbers of nerve involvement increased with the duration of diabetes mellitus. Majority of the patients showed decrease in SNCV and MNCV in more than three nerves,17(32.69%) and 15(28.84%) cases. 14(87.5%) vitamin D deficient patients had HbA1c levels >11.5. Vitamin D deficiency was more pronounced than insufficiency as the HbA1c levels got increased. The vitamin D deficiency increased in proportion to the duration of disease, with maximum number of vitamin D deficient patients in the disease duration of 11-15 years followed by vitamin D deficient patients with duration of disease>15 years. 36(69.2%) of the diabetic patients were deficient in vitamin D, followed by vitamin D insufficiency in 14(26.9%) (p value<0 value=0.314). > Conclusions: Nerve conduction velocities and vitamin D deficiency might be independently associated with diabetic peripheral neuropathy, so these investigative parameters could be used as an independent marker to assess the severity of the neuropathy.

Keywords: Diabetes, Peripheral Neuropathy, Nerve Conduction Velocity, Vitamin D.


How to cite : Alam S, Akhtar K, Abbas S A, Siddiqui S S, Moin S, Relationship of Serum Vitamin D levels with Nerve Conduction Velocity in patients of Diabetic Neuropathy. IP Indian J Neurosci 2020;6(2):96-100


This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.







View Article

PDF File   Full Text Article


Copyright permission

Get article permission for commercial use

Downlaod

PDF File   XML File   ePub File


Digital Object Identifier (DOI)

Article DOI

https://doi.org/10.18231/j.ijn.2020.020


Article Metrics






Article Access statistics

Viewed: 1307

PDF Downloaded: 567



Medical Abbreviation List