Indian Journal of Clinical and Experimental Ophthalmology

Print ISSN: 2395-1443

Online ISSN: 2395-1451

CODEN : IJCEKF

Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...

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Original Article


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20-23


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Prachi Mathur*, Rakesh Porwal


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Comparative study between trabeculectomy with collagen implant versus trabeculectomy with mitomycin C in patients requiring glaucoma surgery at a tertiary care hospital in Rajasthan


Original Article

Author Details : Prachi Mathur*, Rakesh Porwal

Volume : 8, Issue : 1, Year : 2022

Article Page : 20-23

https://doi.org/10.18231/j.ijceo.2022.005



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Abstract

Background: Glaucoma is a chronic multifactorial degenerative optic neuropathy and is the second leading cause of irreversible blindness worldwide. Aim of this study was to study trabeculectomy with collagen implant versus trabeculectomy with mitomycin C in patients requiring glaucoma surgery
Materials and Methods: 50 eyes of 44 patients were assigned randomly to undergo trabeculectomy either with collagen implant (study group) or with MMC (mitomycin C)(control group). Preoperative data included age, gender, IOP (intraocular pressure) and number of preoperative medications. Postoperatively IOP, number of glaucoma medications and postoperative complications if any were recorded on follow up at seven days, one month and three months. Proportion was compared using chi square test while mean using student t test.
Results: Baseline characteristics were matched. The intervention arm had lower IOP post operatively at 3 months (11.84±4.21 vs 17.72±5.93, p = 0.002) but not at day 7 (17.14±9.88 vs 21.37±11.07, p=0.12), 1 month (16.77±11.54 vs 22.91±9.62 p = 0.05); lesser need of anti-glaucoma medication (0.48±0.77 vs 1.95±1.26 p = 0.0001); more complete treatment success (15 vs 7), lower treatment failure (1 vs 4), less Postoperative complications were seen in cases than controls, flat AC(12%vs16%), Hyphema (4% vs 8%); However hypotony were comparable(12%).
Conclusions: This study supports superiority of collagen implant with trabeculectomy as opposed to trabeculectomy with mitomycin C in terms of better clinical outcome and reduced post operative antiglaucoma medications.
 

Keywords: Trabeculectomy, Collagen Implant, Mitomycin C, Anti glaucoma medications


How to cite : Mathur P, Porwal R, Comparative study between trabeculectomy with collagen implant versus trabeculectomy with mitomycin C in patients requiring glaucoma surgery at a tertiary care hospital in Rajasthan. Indian J Clin Exp Ophthalmol 2022;8(1):20-23

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