Indian Journal of Clinical and Experimental Ophthalmology

Print ISSN: 2395-1443

Online ISSN: 2395-1451

CODEN : IJCEKF

Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...

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Original Article


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610-615


Authors Details

Brijesh Sanwaliya*, Sanjeev K Nainiwal, Rakesh Porwal, Akshay Sarraf, Vijaya Sharma


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Placebo-controlled, safety and efficacy study of topical atropine (0.01%) in myopic children


Original Article

Author Details : Brijesh Sanwaliya*, Sanjeev K Nainiwal, Rakesh Porwal, Akshay Sarraf, Vijaya Sharma

Volume : 6, Issue : 4, Year : 2020

Article Page : 610-615

https://doi.org/10.18231/j.ijceo.2020.128



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Abstract

Purpose: To evaluate the safety and efficacy of (0.01%) topical atropine in controlling the progressive myopia in children.
Materials and Methods: Clinical study entitled as Placebo-controlled, safety and efficacy study of (.01%) topical atropine in children with progressive myopia. In this prospective case control study 80 children with regular follow-up were divided into a subgroup of 40 children who received atropine eyedrops (0.01%) every night, and a subgroup of 40 children, who remained untreated, served as controls.
The changes in refraction and axial length of 160 eyes in 80 children were collected and compared for patients treated with 0.01% atropine eyedrop and those with 0.5% carboxymethylcellulose eye drops (control) at 6 months, 12 months and 24 months.
The initial spherical equivalent of refractive status range was between –1.5 and –14.25 DS.
Result: Mean myopia progression for the group of patients treated with 0.01% atropine eye drop was –0.34 ± 0.43 DS/year, significantly lower than that of the control group of –1.08 ± 0.57 DS/year and axial length 0.12+0.23mm/year (cases)compared to controls 0.48+0.29mm/year with p value <0> Conclusion: 0.01% atropine is effective in controlling progression of myopia in children age group 5-16 years with no side effects.

Keywords: Atropine, Axial length, Dioptre sphere, Progressive myopia, Placebo, Spherical equivalent.


How to cite : Sanwaliya B , Nainiwal S K , Porwal R , Sarraf A , Sharma V , Placebo-controlled, safety and efficacy study of topical atropine (0.01%) in myopic children. Indian J Clin Exp Ophthalmol 2020;6(4):610-615

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