Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Original Article
Author Details :
Volume : 6, Issue : 4, Year : 2020
Article Page : 610-615
https://doi.org/10.18231/j.ijceo.2020.128
Abstract
Purpose: To evaluate the safety and efficacy of (0.01%) topical atropine in controlling the progressive myopia in children.
Materials and Methods: Clinical study entitled as Placebo-controlled, safety and efficacy study of (.01%) topical atropine in children with progressive myopia. In this prospective case control study 80 children with regular follow-up were divided into a subgroup of 40 children who received atropine eyedrops (0.01%) every night, and a subgroup of 40 children, who remained untreated, served as controls.
The changes in refraction and axial length of 160 eyes in 80 children were collected and compared for patients treated with 0.01% atropine eyedrop and those with 0.5% carboxymethylcellulose eye drops (control) at 6 months, 12 months and 24 months.
The initial spherical equivalent of refractive status range was between –1.5 and –14.25 DS.
Result: Mean myopia progression for the group of patients treated with 0.01% atropine eye drop was –0.34 ± 0.43 DS/year, significantly lower than that of the control group of –1.08 ± 0.57 DS/year and axial length 0.12+0.23mm/year (cases)compared to controls 0.48+0.29mm/year with p value <0>
Conclusion: 0.01% atropine is effective in controlling progression of myopia in children age group 5-16 years with no side effects.
Keywords: Atropine, Axial length, Dioptre sphere, Progressive myopia, Placebo, Spherical equivalent.
How to cite : Sanwaliya B , Nainiwal S K , Porwal R , Sarraf A , Sharma V , Placebo-controlled, safety and efficacy study of topical atropine (0.01%) in myopic children. Indian J Clin Exp Ophthalmol 2020;6(4):610-615
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