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Update on the role of Eye platelet-rich plasma (E-PRP) in the treatment of ocular surface disorders

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Review Article

Author Details : Bijnya Birajita Panda*, Sumita Mohapatra, Subhabrata Parida

Volume : 6, Issue : 4, Year : 2020

Article Page : 487-496

https://doi.org/10.18231/j.ijceo.2020.106

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Abstract

Platelet rich plasma is the highly concentrated form of autologous human platelets in a small amount of plasma which contains important growth factors and plasma proteins that plays a significant role in wound healing process by epithelial differentiation and collagen bundle organization. In this article, we aim to provide an update on the current literature regarding the Eye Platelet rich plasma, its methods of preparation, physiological and biochemical properties, its clinical applications, safety and efficacy
as compared to other blood derived products etc. In ophthalmology, this product is being used in the management of symptomatic dry eyes, corneal ulcers, periocular chemical and thermal burns, Idiopathic macular hole, Skin rejuvenation post Blepharoplasties and more recently actinic elastosis in the lower eyelid regions. The role of eye platelet rich plasma in Ocular surface disorders has been sparsely studied in literature with more studies and reports on the application of autologous and allogeneic serum eye drops
and therefore, it becomes very important to update ourselves with more studies in this topic to prove the efficiency of this blood derived product. Moreover, the role of other platelet derived products like platelet rich growth factors, platelet lysate in Ocular surface disorders have also been discussed.

Keywords: Dry eye syndrome, Ocular surface disease, Plateletderived products, Platelet rich plasma.

How to cite : Panda B B, Mohapatra S, Parida S, Update on the role of Eye platelet-rich plasma (E-PRP) in the treatment of ocular surface disorders. Indian J Clin Exp Ophthalmol 2020;6(4):487-496

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