Indian Journal of Clinical and Experimental Ophthalmology

Print ISSN: 2395-1443

Online ISSN: 2395-1451

CODEN : IJCEKF

Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...

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Original Article


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159-164


Authors Details

S P Singh, Brijesh Singh Yadav*, K J Singh, Aparajita Chaudhary, Vinod Kumar Singh


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A study to show retinal neurodegeneration association with peripheral nerve conduction in diabetic (Type-II) patients


Original Article

Author Details : S P Singh, Brijesh Singh Yadav*, K J Singh, Aparajita Chaudhary, Vinod Kumar Singh

Volume : 6, Issue : 2, Year : 2020

Article Page : 159-164

https://doi.org/10.18231/j.ijceo.2020.035



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Abstract

Objectives: Aim of this study was to show the association between retinal neuro-degeneration with
peripheral nerve conduction in diabetic (type-II) patients.
Materials and Methods: A total of 30 diabetic patients age ranging from 35-70 years with mild/moderate
non proliferative diabetic retinopathy (NPDR) and 30 non diabetic control were studied at M.D. eye hospital
Prayagraj R.I.O., Prayagraj. Spectral-Domain -OCT imaging was performed with the cirrus HD-OCT
(Version 6.5.0.772; Carl Zeiss Meditec, Inc.), along with nerve conduction study test.
Results: Mean ganglion cell inner Plexiform thickness was assessed in diabetic patients with neuropathy
(Group-A) and without neuropathy (Group-B) in eyes. The difference between mean thickness of these two
groups was found to be significant at same level of significance and confidence interval (t=4.61, p=0.014).
Both the significant difference indicate that diabetic patients with neuropathy (Group A), were associated
with lower mean of “ganglion cell–inner Plexiform thickness” in both the eyes as compared to without
neuropathy patients (Group B).
Conclusion: In this study we found a positive correlation between decrease in Ganglion cell-inner
plexiform layer (GC-IPL) thickness and decrease peripheral nerve conduction in diabetic patients. Decrease
in Ganglion cell-inner plexiform layer (GC -IPL) is predictive of early retinal neurodegeneration in diabetic
patients, according to our study.

Keywords: Diabetic retinopathy, Electrodiagnostic nerve conduction test GC-IPL thickness, Peripheral neuropathy.


How to cite : Singh S P, Yadav B S, Singh K J, Chaudhary A, Singh V K, A study to show retinal neurodegeneration association with peripheral nerve conduction in diabetic (Type-II) patients. Indian J Clin Exp Ophthalmol 2020;6(2):159-164

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