Print ISSN:-2581-5555

Online ISSN:-2456-9542

CODEN : IIJCDU

Article History

Received : 23-03-2022

Accepted : 18-04-2022



Article Metrics




Downlaod Files

   


Article Access statistics

Viewed: 230

PDF Downloaded: 389


Development and validation of UV spectrophotometric method for determination of chlorpropamide in bulk and formulation


Full Text PDF Share on Facebook Share on Twitter


Original Article

Author Details : Shrirang V Kharmate*, Akanksha U. Ingawale, Nilam B. Gurav, Rahul K. Jadhav, Meera U. Kamble, Shubhangi B. Sutar, Sachinkumar V. Patil

Volume : 7, Issue : 3, Year : 2022

Article Page : 163-166

https://doi.org/10.18231/j.ijcaap.2022.033



Suggest article by email

Get Permission

Abstract

The current work focuses on the development and validation of a UV spectrophotometric technique for determining chlorpropamide in bulk and formulation. According to ICH criteria, UV spectrophotometric method was validated for a number of parameters, including linearity, precision, accuracy, sensitivity, limit of detection (LOD), and limit of quantification (LOQ). The maximum wavelength of chlorpropamide was discovered to be 580 nm, and a colorimetric method was created for the quantitative estimation of colour and to quantify the absorbance of a particular wavelength of light by a particular solution. The maximal wavelength of chlorpropamide in the complex mixture was discovered to be 710 nm. The UV spectrophotometric technique and colorimetry are simple, sensitive, accurate, repeatable, and exact. Chlorpropamide in bulk can be determined effectively using the suggested method.
 

Keywords: UV Spectrophotometry, Chlorpropamide, Colorimetry



How to cite : Kharmate S V, Ingawale A U, Gurav N B, Jadhav R K, Kamble M U, Sutar S B, Patil S V, Development and validation of UV spectrophotometric method for determination of chlorpropamide in bulk and formulation. IP Int J Compr Adv Pharmacol 2022;7(3):163-166


This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.