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Comparing the efficacy and haemodynamic response between intrathecal hyperbaric 0.5% bupivacaine with isobaric 0.75% ropivacaine using fentanyl as adjuvant in patients undergoing infra umbilical surgeries

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Original Article

Author Details : R Arun Kumar*, I Preetha

Volume : 7, Issue : 3, Year : 2020

Article Page : 444-449

https://doi.org/10.18231/j.ijca.2020.081

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Abstract

Background: Central neuraxial blockade is the most widely used form of regional anesthesia in surgeries
involving abdominal, urological, obstetric, gynaecological and lower limb. The nerve blocking properties
of the R and S-enantiomers were similar but that the S-enantiomer was less cardiotoxic. The aim of
our study is to compare the efficacy and haemodynamic response between intrathecal hyperbaric 0.5%
Bupivacaine with isobaric 0.75% Ropivacaine using Fentanyl as adjuvant in patients undergoing infra
umbilical surgeries.
Materials and Methods: 60 patients of age group between 25 – 65 years belonging to American Society of
Anaesthesiologist (ASA) 1 and 2 posted for general surgical, urological, orthopaedic and gynaecological
procedures involving lower abdominal surgeries under spinal anaesthesia divided into two groups of 30
each and randomly allocated to one of the two below mentioned groups:
Bupivacaine group (Group B) n=30; Ropivacaine group (Group R) n=30
Observation and Results: Chi-square test and Student’s ‘t’ test were used to analyse the results. The
sensory block in Bupivacaine group B was significantly higher compared to Ropivacaine group R attaining
statistical significance. The 3 minutes motor block, incidence of hypotension was denser and higher in
Bupivacaine group compared with Ropivacaine group. Incidence of bradycardia was not significantly
different between the two groups. Although the onset of motor blockade was denser in Bupivacaine group,
the total duration of motor blockade was similar between the groups.
Conclusion: We conclude from our study that 0.75% isobaric Ropivacaine produces similar duration of
efficacy with stable haemodynamics, as compared with 0.5% hyperbaric Bupivacaine.

Keywords: Bupivacaine, Ropivacaine, Fentanyl, Motor blockade, Infra umbilical surgeries.

How to cite : Kumar R A , Preetha I , Comparing the efficacy and haemodynamic response between intrathecal hyperbaric 0.5% bupivacaine with isobaric 0.75% ropivacaine using fentanyl as adjuvant in patients undergoing infra umbilical surgeries. Indian J Clin Anaesth 2020;7(3):444-449

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