IP Archives of Cytology and Histopathology Research

Print ISSN: 2581-5725

Online ISSN: 2456-9267

CODEN : IACHCL

IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...

Article type

Case Report


Article page

192-194


Authors Details

Manasa G.C*, Shilpa Singh, Vardendra Kulkarni


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Giant phyllodes tumor of breast with diffuse myxoid changes mimicking low- grade fibromyxoid sarcoma (LGFMS) - A case report


Case Report

Author Details : Manasa G.C*, Shilpa Singh, Vardendra Kulkarni

Volume : 7, Issue : 3, Year : 2022

Article Page : 192-194

https://doi.org/10.18231/j.achr.2022.042



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Abstract

Objective: Phyllodes tumors are biphasic tumors consisting of epithelial and stromal components that account for less than 1% of all breast tumors. Phyllodes tumors are rare that behave in an unpredictable manner and can rarely have diffuse myxoid changes without an exaggerated intracanalicular pattern with leaf like fronds and stromal hypercellularity.
Case Report: 50-year old lady with left breast lump, morphologically mimicking low grade fibromyxoid sarcoma was finally diagnosed as recurrent phyllodes tumor (intermediate grade) with extensive myxoid change, based on the previous microscopic finding of phyllodes tumor and excluded diagnosis of low grade fibromyxoid sarcoma by MUC4 stain.
Conclusion: Recurrent phyllodes tumor which is a common stromal tumor was diagnosed as LGFMS because of its morphology change resembling, LGFMS which was ruled later out with sensitive and specific marker for LGFMS i.e., MUC4.
 

Keywords: Fibroepithelial lesion, Phyllodes tumor breast, LGFMS, MUC4


How to cite : G.c M , Singh S, Kulkarni V, Giant phyllodes tumor of breast with diffuse myxoid changes mimicking low- grade fibromyxoid sarcoma (LGFMS) - A case report. IP Arch Cytol Histopathol Res 2022;7(3):192-194

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