IP Archives of Cytology and Histopathology Research

Print ISSN: 2581-5725

Online ISSN: 2456-9267

CODEN : IACHCL

IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...

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Original Article


Article page

164-170


Authors Details

Suvernkar Suparna Vishwanath, Vishal Rajput*, Deepa Rajput, Nitin Wathore


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A study of clinico-histopathological correlation in leprosy


Original Article

Author Details : Suvernkar Suparna Vishwanath, Vishal Rajput*, Deepa Rajput, Nitin Wathore

Volume : 7, Issue : 3, Year : 2022

Article Page : 164-170

https://doi.org/10.18231/j.achr.2022.036



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Abstract

Introduction: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. It principally affects the cooler parts of the body, mainly skin and peripheral nerves; it also involves muscles, eyes, bones, testis and internal organs. Histopathological study of leprosy is very important in understanding the disease, its varied manifestations and complications. Clinical diagnosis of early leprosy lesions offer difficulties even to experienced dermatologists and leprologists. A definitive diagnosis may be possible by histopathological examination. Histological diagnosis when available is deemed the gold standard for diagnosis of leprosy.
Aims : To diagnose the case of leprosy using skin biopsy specimen. To study the clinical and histopathological correlation among leprosy patients attending a tertiary referral center. To classify the lesion according to Ridley and Jopling (RJ) classification.
Materials and Methods: The present study was conducted over a period of 18 months from Jan 2019 to July 2020. Total 51 new suspected cases were selected on clinical ground attending dermatological OPD. These patients were subjected to skin biopsy. Histopathological classification done on the basis of Riedly- Jopling criteria.
Out of total 51 cases 40 cases showing leprosy changes on histopathological examination.Majority of the patients were males (53.06%), while females (46.94%) constituted a minority with male to female ratio of 1.1:1.
Both clinically and histopathologically BT constituted the predominant group (62.7%) and (54.7%) respectively, followed by LL (15.6%).
Conclusion: Clinical diagnosis of early leprosy lesions offer difficulties even to experienced dermatologists and leprologists. A definitive diagnosis may be possible by histopathological & bacteriological examination.
 

Keywords: Leprosy, Clinico­histopathological correlation, Riedly Jopling Criterion


How to cite : Vishwanath S S, Rajput V, Rajput D, Wathore N, A study of clinico-histopathological correlation in leprosy. IP Arch Cytol Histopathol Res 2022;7(3):164-170

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