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Descriptive analysis of histopathological diagnosis of lymph node biopsies at a Tertiary Referral Center

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Original Article

Author Details : Amrita , Vijay Yadav, Manoj Kumar Gupta*, Sanjay Kumar

Volume : 5, Issue : 3, Year : 2020

Article Page : 203-208

https://doi.org/10.18231/j.achr.2020.045

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Abstract

Backgraound: Lymphadenopathy is a common clinical problem and biopsies done to know the cause of nodal enlargement may be neoplastic or non-neoplastic. Neoplastic lesions are mainly lymphohematogenous malignancies and metastases while non-neoplastic lymphadenopathies are varied. This study was undertaken to determine the histopathological spectrum of lymphadenectomies.
Materials and Methods: This was a descriptive study wherein 516 cases of histologically diagnosed peripheral lymph node biopsies from Aug 2016 to July 2019 were reviewed. Surgical resection specimens with lymph node dissection were excluded from the study.
Results: Neoplastic lesions were 47.68% (246 cases) consist of 21.5% (111 cases) of non-Hodgkin lymphoma, 17.6% (91 cases) of Hodgkin lymphoma and 8.5% (44 cases) of metastatic lesions. The nonneoplastic lesions were 52.32% (270 cases), which included 21.1% (109 cases) of tuberculosis followed by follicular hyperplasia, 9.5% (49 cases), chronic lymphadenitis 8.9% (46 cases).
Conclusions: Lymphoma was the most common cause of biopsied lymphadenopathy in our study (NHL comprising 21.5% and HL comprising 17.6%) followed by tubercular lymphadenitis (21.1%).

Keywords: Lymph Node, Non-neoplastic diseases, Hodgkin lymphoma, Non Hodgkin lymphoma.

How to cite : Amrita, Yadav V, Gupta M K, Kumar S, Descriptive analysis of histopathological diagnosis of lymph node biopsies at a Tertiary Referral Center. IP Arch Cytol Histopathol Res 2020;5(3):203-208

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