IP Archives of Cytology and Histopathology Research

Print ISSN: 2581-5725

Online ISSN: 2456-9267

CODEN : IACHCL

IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...

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147-153


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Rajeshwari K*, N V Dravid, Karibassappa G. N, Chakor Rokade


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Non-infectious granulomatous dermatitis –a histomorphological study at a tertiary care centre


Original Article

Author Details : Rajeshwari K*, N V Dravid, Karibassappa G. N, Chakor Rokade

Volume : 5, Issue : 2, Year : 2020

Article Page : 147-153

https://doi.org/10.18231/j.achr.2020.030



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Abstract

Background: Non-infectious granulomatous dermatitis is a distinctive reactive inflammatory condition.
They are relatively difficult to diagnosis and distinguish both clinically and histologically and most of them
are associated with systemic diseases that impact on the overall prognosis. Present study aims at classifying
the non-infectious granulomatous dermatitis based on morphology of granulomas, for making an accurate
diagnosis. The definitive diagnosis of the granulomatous lesions of skin with identification of etiological
agent is very essential for specific treatment and an appropriate desirable outcome.
Aims and Objectives: To study the histomorphology of various non- infectious granulomatous dermatitis
of skin and classify them, accordingly into different categories.
Materials and Methods: A total of 2,690 skin biopsies received to the department of pathology over a
period of five year (Jan 2011-Jan 2016) were objectively reviewed using different staining technique. Noninfectious
granulomatous dermatitis were identified and classified into different types based on morphology,
etiology and also compared among different age groups and genders.
Results: Out of total 2,690 skin biopsies received, 314 cases exhibited granulomatous reaction pattern.
Among the granulomatous lesions of skin, non-infectious granulomas were seen in 77 cases (2.8%). Among
the non-infectious granulomas majority of the cases were mixed cell granuloma seen in 45 cases (58.44%),
palisading granuloma in 19 cases (24.67 %), non-specific granulomas/miscellaneous in 10 cases (13 %)
and epithelioid cell granuloma without necrosis granulomas in 3 cases (3.9 %).
Conclusions: Knowledge of histomorphology of non-infectious granulomatous dermatitis is very important
to understand and detect the early and old lesions of dermatitis. This helps in guiding and planning the
therapeutic approaches of the dermatitis.

Keywords: Histomorphology, Skin, Foreign body, Rheumatoid nodule.


How to cite : Rajeshwari K, Dravid N V, Karibassappa G. N, Rokade C, Non-infectious granulomatous dermatitis –a histomorphological study at a tertiary care centre. IP Arch Cytol Histopathol Res 2020;5(2):147-153

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