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Desquamative Diseases and Periodontal Health/Treatment

  • Systemic Diseases (N Buduneli, Section Editor)
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Abstract

Purpose of Review

The purpose of the present review is to answer the following focused question: “What are the most relevant findings about the diagnosis and subsequent treatment of desquamative gingivitis (DG)?”

Recent Findings

Topical corticosteroids in the form of gel should be the first-line medical treatment and may be sufficient for some moderate or mild forms of DG. When patients continue to experience erosions and pain despite topical therapy, treatment with systemic therapy is indicated. A tailored plaque control program is effective in reducing gingival manifestations of DG in terms of related symptoms, plaque index, mucosal disease score, gingival crevicular fluid volume, matrix metalloproteinase (MMP)-1, and MMP-9.

Summary

The painful symptoms and clinical features in gingiva are improved by non-traumatic oral hygiene procedures, but the underlying causes of DG cannot be eliminated by plaque control alone. Thus, the cooperation with dermatologists/oral pathologists is always required. New technologies for home oral hygiene may improve patients’ quality of life.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Prinz H. Chronic diffuse desquamative gingivitis. Dent Cosm. 1932;74:332–3.

    Google Scholar 

  2. •• Caton JG, Armitage G, Berglundh T, Chapple ILC, Jepsen S, Kornman KS, et al. A new classification for periodontal and peri-implant diseases and conditions—introduction and key changes from the 1999 classification. J Clin Periodontol. 2018;45(Suppl 20):1–8. https://doi.org/10.1111/jcpe.12935Thismanuscript reports the update of the 1999 classification.

    Article  Google Scholar 

  3. Jascholt I, Lai O, Zillikens D, Kasperkiewicz M. Periodontitis in oral pemphigus and pemphigoid: a systematic review of published studies. J Am Acad Dermatol. 2017;76:975–8.e3. https://doi.org/10.1016/j.jaad.2016.10.028.

    Article  PubMed  Google Scholar 

  4. Tricamo MB, Rees TD, Hallmon WW, Wright JM, Cueva MA, Plemons JM. Periodontal status in patients with gingival mucous memebrane pemphigoid. J Periodontol. 2006;77:398–405. https://doi.org/10.1902/jop.2006.050113.

    Article  PubMed  Google Scholar 

  5. Ramon-Fluixa C, Bagan-Sebastian J, Milian-Masanet M, Scully C. Periodontal status in patients with oral lichen planus: a study of 90 cases. Oral Dis. 1999;5:303–6. https://doi.org/10.1111/j.1601-0825.1999.tb00094.x.

    Article  CAS  PubMed  Google Scholar 

  6. Bystryn JC, Rudolph JL. Pemphigus. Lancet. 2005;366:61–73. https://doi.org/10.1016/S0140-6736(05)66829-8.

    Article  PubMed  Google Scholar 

  7. Beeraka SS, Natarajan K, Patil R, Manne RK, Sarath Prathi VS, Kumar Kolaparthi VS. Clinical and radiological assessment of effects of long-term corticosteroid therapy on oral health. Dent Res J (Isfahan). 2013:666–73.

  8. Hajishengallis G. Periodontitis: from microbial immune subversion to systemic inflammation. Nat Rev Immunol. 2015;15:30–44. https://doi.org/10.1038/nri3785.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Scully C, Carrozzo M, Gandolfo S, Puiatti P, Monteil R. Update on mucous membrane pemphigoid: a heterogeneous immune-mediated subepithelial blistering entity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88:56–68. https://doi.org/10.1016/s1079-2104(99)70194-0.

    Article  CAS  PubMed  Google Scholar 

  10. Bagan J, Lo Muzio L, Scully C. Mucosal disease series. Number III. Mucous membrane pemphigoid. Oral Dis. 2005;11:197–218. https://doi.org/10.1111/j.1601-0825.2005.01140.x.

    Article  CAS  PubMed  Google Scholar 

  11. Mollaoglu N. Oral lichen planus: a review. Br J Oral Maxillofac Surg. 2000;38:370–7. https://doi.org/10.1054/bjom.2000.0335.

    Article  CAS  PubMed  Google Scholar 

  12. Eisen D, Carrozzo M, Bagan Sebastian JV, Thongprasom K. Number V Oral lichen planus: clinical features and management. Oral Dis. 2005;11:338–49. https://doi.org/10.1111/j.1601-0825.2005.01142.x.

    Article  CAS  PubMed  Google Scholar 

  13. Korman N. Pemphigus. J Am Acad Dermatol. 1988;18:1219–38. https://doi.org/10.1016/s0190-9622(88)70128-0.

    Article  CAS  PubMed  Google Scholar 

  14. Black M, Mignogna MD, Scully C. Number II. Pemphigus vulgaris. Oral Dis. 2005;11:119–30. https://doi.org/10.1111/j.1601-0825.2005.01139.x.

    Article  CAS  PubMed  Google Scholar 

  15. Scully C, Porter SR. The clinical spectrum of desquamative gingivitis. Semin Cutan Med Surg. 1997;16:308–13. https://doi.org/10.1016/s1085-5629(97)80021-1.

    Article  CAS  PubMed  Google Scholar 

  16. Farthing P, Bagan JV, Scully C. Mucosal disease series. Number IV Erythema multiforme Oral Dis. 2005;11:261–7. https://doi.org/10.1111/j.1601-0825.2005.01141.x.

    Article  CAS  PubMed  Google Scholar 

  17. Ayangco L, Rogers RS 3rd. Oral manifestations of erythema multiforme. Dermatol Clin. 2003;21:195–205. https://doi.org/10.1016/s0733-8635(02)00062-1.

    Article  PubMed  Google Scholar 

  18. Jorizzo JL, Salisbury PL, Rogers RS 3rd, Goldsmith SM, Shar GG, Callen JP, et al. Oral lesions in systemic lupus erythematosus. Do ulcerative lesions represent a necrotizing vasculitis? J Am Acad Dermatol. 1992;27:389–94. https://doi.org/10.1016/0190-9622(92)70204-s.

    Article  CAS  PubMed  Google Scholar 

  19. Sarzi-Puttini P, Atzeni F, Iaccarino L, Doria A. Environment and systemic lupus erythematosus: an overview. Autoimmunity. 2005;38:465–72. https://doi.org/10.1080/08916930500285394.

    Article  CAS  PubMed  Google Scholar 

  20. Horwitz ME, Sullivan KM. Chronic graft-versus-host disease. Blood Rev. 2006;20:15–27. https://doi.org/10.1016/j.blre.2005.01.007.

    Article  PubMed  Google Scholar 

  21. Sato M, Tokuda N, Fukumoto T, Mano T, Sato T, Ueyama Y. Immunohistopathological study of the oral lichenoid lesions of chronic GVHD. J Oral Pathol Med. 2006;35:33–6. https://doi.org/10.1111/j.1600-0714.2005.00372.x.

    Article  CAS  PubMed  Google Scholar 

  22. Lorenzana ER, Rees TD, Glass M, Detweiler JG. Chronic ulcerative stomatitis: a case report. J Periodontol. 2000;71:104–11. https://doi.org/10.1902/jop.2000.71.1.104.

    Article  CAS  PubMed  Google Scholar 

  23. Lewis JE, Beutner EH, Rostami R, Chorzelski TP. Chronic ulcerative stomatitis with stratified epithelium-specific antinuclear antibodies. Int J Dermatol. 1996;35:272–5. https://doi.org/10.1111/j.1365-4362.1996.tb03000.x.

    Article  CAS  PubMed  Google Scholar 

  24. Roman CC, Yuste CM, Gonzalez MA, Gonzalez AP, Lopez G. Plasma cell gingivitis. Cutis. 2002;69:41–5.

    PubMed  Google Scholar 

  25. Porter SR, Scully C, Midda M, Eveson JW. Adult linear immunoglobulin A disease manifesting as desquamative gingivitis. Oral Surg Oral Med Oral Pathol. 1990;70:450–3. https://doi.org/10.1016/0030-4220(90)90208-a.

    Article  CAS  PubMed  Google Scholar 

  26. Porter SR, Bain SE, Scully CM. Linear IgA disease manifesting as recalcitrant desquamative gingivitis. Oral Surg Oral Med Oral Pathol. 1992;74:179–82. https://doi.org/10.1016/0030-4220(92)90379-5.

    Article  CAS  PubMed  Google Scholar 

  27. O’Regan E, Bane A, Flint S, Timon C, Toner M. Linear IgA disease presenting as desquamative gingivitis: a pattern poorly recognized in medicine. Arch Otolaryngol Head Neck Surg. 2004;130:469–72. https://doi.org/10.1001/archotol.130.4.469.

    Article  PubMed  Google Scholar 

  28. Economopoulou P, Laskaris G. Dermatitis herpetiformis: oral lesions as an early manifestation. Oral Surg Oral Med Oral Pathol. 1986;62:77–80. https://doi.org/10.1016/0030-4220(86)90074-5.

    Article  CAS  PubMed  Google Scholar 

  29. Collin P, Reunala T. Recognition and management of the cutaneous manifestations of celiac disease: a guide for dermatologists. Am J Clin Dermatol. 2003;4:13–20. https://doi.org/10.2165/00128071-200304010-00002.

    Article  PubMed  Google Scholar 

  30. Campos M, Silvente C, Lecona M, Suarez R, Lazaro P. Epidermolysis bullosa acquisita: diagnosis by fluorescence overlay antigen mapping and clinical response to high-dose intravenous immunoglobulin. Clin Exp Dermatol. 2006;31:71–3. https://doi.org/10.1111/j.1365-2230.2005.01989.x.

    Article  CAS  PubMed  Google Scholar 

  31. Tilakaratne W, Dissanayake M. Paraneoplastic pemphigus: a case report and review of literature. Oral Dis. 2005;11:326–9. https://doi.org/10.1111/j.1601-0825.2005.01116.x.

    Article  PubMed  Google Scholar 

  32. Wade MS, Black MM. Paraneoplastic pemphigus: a brief update. Australas J Dermatol. 2005;46:1–8 quiz 9–10.

    Article  Google Scholar 

  33. Coelho S, Reis JP, Tellechea O, Figueiredo A, Black M. Paraneoplastic pemphigus with clinical features of lichen planus associated with low-grade B cell lymphoma. Int J Dermatol. 44:366–71. https://doi.org/10.1111/j.1365-4632.2004.02526.x.

  34. Gravitis K, Daley TD, Lochhead MA. Management of patients with foreign body gingivitis: report of 2 cases with histologic findings. J Can Dent Assoc. 2005;71:105–9.

    PubMed  Google Scholar 

  35. Zhu JF, Kaminski MJ, Pulitzer DR, Hu J, Thomas HF. Psoriasis: pathophysiology and oral manifestations. Oral Dis. 1996;2:135–44. https://doi.org/10.1111/j.1601-0825.1996.tb00214.x.

    Article  CAS  PubMed  Google Scholar 

  36. Brice DM, Danesh-Meyer MJ. Oral lesions in patients with psoriasis: clinical presentation and management. J Periodontol. 2000;71:1896–903. https://doi.org/10.1902/jop.2000.71.12.1896.

    Article  CAS  PubMed  Google Scholar 

  37. Mariotti A. Desquamative gingivitis: revisited. Todays FDA. 1991;3:1C–2C.

    CAS  PubMed  Google Scholar 

  38. Lo Russo L, Fedele S, Guiglia R, Ciavarella D, Lo Muzio L, Gallo P, et al. Diagnostic pathways and clinical significance of desquamative gingivitis. J Periodontol. 2008;79:4–24. https://doi.org/10.1902/jop.2008.070231.

    Article  PubMed  Google Scholar 

  39. Vaillant L, Arbeille B, Goga D, de Muret A, Prime A, Lorette G. Cicatricial pemphigoid disclosed by superficial desquamative gingivitis. Clinical and immuno-electron microscopic study of a case (in French). Ann Dermatol Venereol. 1990;117:613–20.

    CAS  PubMed  Google Scholar 

  40. Mignogna MD, Lo Muzio L, Bucci E. Clinical features of gingival pemphigus vulgaris. J Clin Periodontol. 2001;28:489–93. https://doi.org/10.1034/j.1600-051x.2001.028005489.x.

    Article  CAS  PubMed  Google Scholar 

  41. Stoopler ET, Sollecito TP, DeRossi SS. Desquamative gingivitis: early presenting symptom of mucocutaneous disease. Quintessence Int. 2003;34:582–6.

    PubMed  Google Scholar 

  42. Mignogna MD, Lo Russo L, Fedele S. Gingival involvement of oral lichen planus in a series of 700 patients. J Clin Periodontol. 2005;32:1029–33. https://doi.org/10.1111/j.1600-051X.2004.00761.x.

    Article  PubMed  Google Scholar 

  43. Al-Abeedi F, Aldahish Y, Almotawa Z, Kujan O. The differential diagnosis of desquamative gingivitis: review of the literature and clinical guide for dental undergraduates. Int Oral Health. 2015;7(Suppl 1):88–92.

    Google Scholar 

  44. Scully C, Carrozzo M. Oral mucosal disease: lichen planus. Br J Oral Maxillofac Surg. 2008;46:15–21. https://doi.org/10.1016/j.bjoms.2007.07.199.

    Article  PubMed  Google Scholar 

  45. Al-Hashimi I, Schiffer M, Lockhart PB, Wray D, Brennan M, Migliorati CA, et al. Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103(Suppl):S25.e1–12. https://doi.org/10.1016/j.tripleo.2006.11.001.

    Article  Google Scholar 

  46. Leao JC, Ingafou M, Khan A, Scully C, Porter S. Desquamative gingivitis: retrospective analysis of disease associations of a large cohort. Oral Dis. 2008;14:556–60. https://doi.org/10.1111/j.1601-0825.2007.01420.x.

    Article  CAS  PubMed  Google Scholar 

  47. Alrashdan MS, Cirillo N, McCullough M. Oral lichen planus: a literature review and update. Arch Dermatol Res. 2016;308:539–51. https://doi.org/10.1007/s00403-016-1667-2.

    Article  PubMed  Google Scholar 

  48. Carrozzo M, Porter S, Mercadante V, Fedele S. Oral lichen planus: a disease or spectrum of tissue reaction? Types, causes, diagnostic algorithms, prognosis, management strategies. Periodontol. 2019;80:105–25. https://doi.org/10.1111/prd.12260.

    Article  Google Scholar 

  49. Bilodeau EA, Lalla RV. Recurrent oral ulceration: etiology, classification, management and diagnostic algorithm. Periodontol. 2019;80:49–60. https://doi.org/10.1111/prd.12262.

    Article  Google Scholar 

  50. Rich AM, Seo B, Parachuru V, Hussaini HM. The nexus between periodontics and oral pathology. Periodontol. 2017;74:176–81. https://doi.org/10.1111/prd.12197.

    Article  Google Scholar 

  51. Yamanaka Y, Yamashita M, Innocentini LMA, Macedo LD, Chahud F, Ribeiro-Silva A, et al. Direct immunofluorescence as a helpful tool for the differential diagnosis of oral lichen planus and oral lichenoid lesions. Am J Dermatopathol. 2018;40:491–7. https://doi.org/10.1097/DAD.0000000000001071.

    Article  PubMed  Google Scholar 

  52. Fitzpatrick SG, Hirsch SA, Gordon SC. The malignant transformation of oral lichen planus and oral lichenoid lesions: a systematic review. J Am Dent Assoc. 2014;145:45–6. https://doi.org/10.14219/jada.2013.10.

    Article  PubMed  Google Scholar 

  53. Scully C, Lo ML. Oral mucosal diseases: mucous membrane pemphigoid. Br J Oral Maxillofac Surg. 2008;46:358–66. https://doi.org/10.1016/j.bjoms.2007.07.200.

    Article  PubMed  Google Scholar 

  54. Laskaris G, Satriano RA. Drug-induced blistering oral lesions. Clin Dermatol. 1993;11:545–50. https://doi.org/10.1016/0738-081x(93)90164-8.

    Article  CAS  PubMed  Google Scholar 

  55. Higgins GT, Allan RB, Hall R, Field EA, Kaye SB. Development of ocular disease in patients with mucous membrane pemphigoid involving the oral mucosa. Br J Ophthalmol. 2006;90:964–7. https://doi.org/10.1136/bjo.2006.092528.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  56. Scully C, Mignogna M. Oral mucosal disease: pemphigus. Br J Oral Maxillofac Surg. 2008;46:272–7. https://doi.org/10.1016/j.bjoms.2007.07.205.

    Article  PubMed  Google Scholar 

  57. Jukić IL, Marinović B. Significance of immunofluorescence in the diagnosis of autoimmune bullous dermatoses. Clin Dermatol. 2011;29:389–97. https://doi.org/10.1016/j.clindermatol.2011.01.008.

    Article  PubMed  Google Scholar 

  58. Mignogna MD, Fortuna G, Leuci S, Ruoppo E, Marasca F, Matarasso S. Nikolsky’s sign on the gingival mucosa: a clinical tool for oral health practitioners. J Periodontol. 2008;79:2241–6. https://doi.org/10.1902/jop.2008.080217.

    Article  PubMed  Google Scholar 

  59. Endo H, Rees TD, Allen EP, Kuyama K, Aoki S, Yamamoto H, et al. A stab-and-roll biopsy technique to maintain gingival epithelium for desquamative gingivitis. J Periodontol. 2014;85:802–9. https://doi.org/10.1902/jop.2014.130428.

    Article  PubMed  Google Scholar 

  60. Leuci S, Ruoppo E, Adamo D, Calabria E, Mignogna MD. Oral autoimmune vesicobullous diseases: classification, clinical presentation, molecular mechanisms, diagnostic algorithms, and management. Periodontol. 2019;80:77–88. https://doi.org/10.1111/prd.12263.

    Article  Google Scholar 

  61. •• Maderal AD, Lee Salisbury P, Jorizzo JL. Desquamative gingivitis: diagnosis and treatment. J Am Acad Dermatol. 2018;78:851–61. https://doi.org/10.1016/j.jaad.2017.04.1140This manuscript reports guidelines for clinical management of desquamative gingivitis.

    Article  PubMed  Google Scholar 

  62. Cribier B, Frances C, Chosidow O. Treatment of lichen planus. An evidence-based medicine analysis of efficacy. Arch Dermatol. 1998;134:1521–30. https://doi.org/10.1001/archderm.134.12.1521.

    Article  CAS  PubMed  Google Scholar 

  63. Carrozzo M, Gandolfo S. The management of oral lichen planus. Oral Dis. 1999;5:196–205. https://doi.org/10.1111/j.1601-0825.1999.tb00301.x.

    Article  CAS  PubMed  Google Scholar 

  64. Eisen D, Carrozzo M, Bagan Sebastian JV, Thongprasom K. Oral lichen planus: clinical features and management. Oral Dis. 2005;11:338–49. https://doi.org/10.1111/j.1601-0825.2005.01142.x.

    Article  CAS  PubMed  Google Scholar 

  65. Lodi G, Scully C, Carrozzo M, Griffiths M, Sugerman PB, Thongprasom K. Current controversies in oral lichen planus: report of an international consensus meeting. Part 2. Clinical management and malignant transformation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100:164–78. https://doi.org/10.1016/j.tripleo.2004.06.077.

    Article  PubMed  Google Scholar 

  66. Carrozzo M, Thorpe R. Oral lichen planus: a review. Minerva Stomatol. 2009;58:519–37.

    CAS  PubMed  Google Scholar 

  67. Cheng S, Kirtschig G, Cooper S, Thornhill M, Leonardi-Bee J, Murphy R. Interventions for erosive lichen planus affecting mucosal sites. Cochrane Database Syst Rev. 2012;2:CD008092. https://doi.org/10.1002/14651858.CD008092.pub2.

    Article  Google Scholar 

  68. Lozada-Nur F, Miranda C. Oral lichen planus: epidemiology, clinical characteristics, and associated diseases. Semin Cutan Med Surg. 1997;16:273–7. https://doi.org/10.1016/s1085-5629(97)80016-8.

    Article  CAS  PubMed  Google Scholar 

  69. Robinson NA, Wray D. Desquamative gingivitis: a sign of mucocutaneus disorders—a review. Australian Dental J. 2003;48:206–11. https://doi.org/10.1111/j.1834-7819.2003.tb00033.x.

    Article  CAS  Google Scholar 

  70. García-Pola MJ, Gonzalez-Alvarez L, Garcia-Martin JR. Tratamiento del liquen plano oral. Revisión sistemática y protocolo de actuación. Med Clin (Barc). 2017;149:351–62. https://doi.org/10.1016/j.medcli.2017.06.024.

    Article  Google Scholar 

  71. Chauhan P, De D, Handa S, Narang T, Saikia UN. A prospective observational study to compare efficacy of topical triamcinolone acetonide 0.1% oral paste, oral methotrexate, and a combination of topical triamcinolone acetonide 0.1% and oral methotrexate in moderate to severe oral lichen planus. Dermatol Ther. 2018;31(1). https://doi.org/10.1111/dth.12563.

  72. Akram Z, Abduljabbar T, Vohra F, Javed F. Efficacy of low level laser therapy compared to steroid therapy in the treatment of oral lichen planus: a systematic review. J Oral Pathol Med. 2018;47:11–7. https://doi.org/10.1111/jop.12619.

    Article  CAS  PubMed  Google Scholar 

  73. Buonavoglia A, Leone P, Dammacco R, Di Lernia G, Petruzzi M, Bonamonte D, et al. Pemphigus and mucous membrane pemphigoid: an update from diagnosis to therapy. Autoimmun Rev. 2019;18:349–58. https://doi.org/10.1016/j.autrev.2019.02.005.

    Article  PubMed  Google Scholar 

  74. Kridin K, Kneiber D, Kowalski EH, Valdebran M, Amber KT. Epidermolysis bullosa acquisita: a comprehensive review. Autoimmun Rev. 2019;18:786–95. https://doi.org/10.1016/j.autrev.2019.06.007.

    Article  PubMed  Google Scholar 

  75. De Risi-Puglisi T, Sbidian E, Ingen-Housz-Oro S, Le Cleach L. Intervention for erythema multiforme: a systematic review. J Eur Acad Dermatol Venereol. 2019;33:842–9. https://doi.org/10.1111/jdv.15447.

    Article  Google Scholar 

  76. Stone SJ, Heasman PA, Staines KS, McCracken GI. The impact of structured plaque control for patients with gingival manifestations of oral lichen planus: a randomized controlled study. J Clin Periodontol. 2015;42:356–62. https://doi.org/10.1111/jcpe.12385.

    Article  PubMed  Google Scholar 

  77. • Cabras M, Gambino A, Broccoletti R, Arduino PG. Desquamative gingivitis: a systematic review of possible treatments. J Biol Regul Homeost Agents. 2019;33:637–42 This is the only systematic review about treatment strategies of desquamative gingivitis.

    CAS  PubMed  Google Scholar 

  78. Arduino PG. Oral complications of dermatologic disorders. Atlas Oral Maxillofac Surg Clin North Am. 2017;25:221–8. https://doi.org/10.1016/j.cxom.2017.04.013.

    Article  PubMed  Google Scholar 

  79. Mustafa MB, Porter SR, Smoller BR, Sitaru C. Oral mucosa manifestations of autoimmune skin diseases. Autoimmun Rev. 2015;14:930–51. https://doi.org/10.1016/j.autrev.2015.06.005.

    Article  PubMed  Google Scholar 

  80. Ertugrul AS, Dursun R, Dundar N, Avunduk MC, Hakki SS. MMP-1, MMP-9, and TIMP-1 levels in oral lichen planus patients with gingivitis and periodontitis. Arch Oral Biol. 2013;58:843–52. https://doi.org/10.1016/j.archoralbio.2013.01.015.

    Article  CAS  PubMed  Google Scholar 

  81. Arduino PG, Romano F, Sasia D, Broccoletti R, Ricceri F, Barbui AM, et al. Subgingival microbiota in White patients with desquamative gingivitis: a cross-sectional study. J Periodontol. 2017;88:643–50. https://doi.org/10.1902/jop.2017.160745.

    Article  PubMed  Google Scholar 

  82. Salgado DS, Jeremias F, Capela MV, Onofre MA, Massucato EM, Orrico SR. Plaque control improves the painful symptoms of oral lichen planus gingival lesions. A short-term study. J Oral Pathol Med. 2013;42:728–32. https://doi.org/10.1111/jop.12093.

    Article  PubMed  Google Scholar 

  83. Stone SJ, McCracken GI, Heasman PA, Staines KS, Pennington M. Cost-effectiveness of personalized plaque control for managing the gingival manifestations of oral lichen planus: a randomized controlled study. J Clin Periodontol. 2013;40:859–67. https://doi.org/10.1111/jcpe.12126.

    Article  PubMed  Google Scholar 

  84. Dentino AR, Derderian G, Wolf M, Cugini M, Johnson R, Van Swol RL, et al. Six-month comparison of powered versus manual toothbrushing for safety and efficacy in the absence of professional instruction in mechanical plaque control. J Periodontol. 2002;73:770–8. https://doi.org/10.1902/jop.2002.73.7.770.

    Article  PubMed  Google Scholar 

  85. Hope CK, Petrie A, Wilson M. In vitro assessment of the plaque-removing ability of hydrodynamic shear forces produced beyond the bristles by 2 electric toothbrushes. J Periodontol. 2003;74:1017–22. https://doi.org/10.1902/jop.2003.74.7.1017.

    Article  PubMed  Google Scholar 

  86. Stanford CM, Srikantha R, Wu CD. Efficacy of the Sonicare toothbrush fluid dynamic action on removal of human supragingival plaque. J Clin Dent. 1997;8:10–4.

    CAS  PubMed  Google Scholar 

  87. • Bianco L, Romano F, Maggiora M, Bongiovanni L, Guzzi N, Curmei E, et al. Effect of sonic versus manual supervised toothbrushing on both clinical and biochemical profiles of patients with desquamative gingivitis associated with oral lichen planus: a randomized controlled trial. Int J Dent Hygiene. 2019;17:161–9. https://doi.org/10.1111/idh.12377This randomized clinical trial reports the efficacy of the supervised plaque control with sonic toothbrushing.

    Article  Google Scholar 

  88. Romano F, Arduino PG, Maggiora M, Curmei E, Manavella V, Broccoletti R, et al. Effect of a structured plaque control on MMP-1 and MMP-9 crevicular levels in patients with desquamative gingivitis associated with oral lichen planus. Clin Oral Investig. 2019;23:2651–8. https://doi.org/10.1007/s00784-018-2704-7.

    Article  PubMed  Google Scholar 

  89. Holmstrup P, Schiøtz AW, Westergaard J. Effect of dental plaque control on gingival lichen planus. Oral Surg Oral Med Oral Pathol. 1990;69:585–90. https://doi.org/10.1016/0030-4220(90)90241-j.

    Article  CAS  PubMed  Google Scholar 

  90. Guiglia R, di Liberto C, Pizzo G, Picone L, Lo Muzio L, Gallo PD, et al. A combined treatment regimen for desquamative gingivitis in patients with oral lichen planus. J Oral Pathol Med. 2007;36:110–6. https://doi.org/10.1111/j.1600-0714.2007.00478.x.

    Article  CAS  PubMed  Google Scholar 

  91. Lopez-Jornet P, Camacho-Alonso F. Application of a motivation-behavioral skills protocol in gingival lichen planus: a short-term study. J Periodontol. 2010;81:1449–54. https://doi.org/10.1902/jop.2010.100245.

    Article  PubMed  Google Scholar 

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Author notes

  1. Federica Romano and Filippo Citterio equally contributed to the manuscript.

Authors and Affiliations

  1. Section of Periodontology, C.I.R Dental School, Department of Surgical Sciences, University of Turin, Turin, Italy

    Federica Romano, Filippo Citterio, Laura Bianco & Mario Aimetti

  2. Turin, Italy

    Valeria Manavella

Authors
  1. Federica Romano
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  2. Filippo Citterio
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  3. Valeria Manavella
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  4. Laura Bianco
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  5. Mario Aimetti
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Corresponding author

Correspondence to Mario Aimetti.

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This narrative review was self-funded. The authors report no conflicts of interest related to this study.

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Romano, F., Citterio, F., Manavella, V. et al. Desquamative Diseases and Periodontal Health/Treatment. Curr Oral Health Rep 7, 129–138 (2020). https://doi.org/10.1007/s40496-020-00263-5

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