Skip to main content
SpringerLink
Log in

DNA self-assembly: prospectus and its future application

  • Review
  • Published:
Journal of Materials Science Aims and scope Submit manuscript

Abstract

The field of DNA nanotechnology has grown rapidly in the past 10 years, with many baby steps and exciting breakthroughs. DNA has recently been emerged as a versatile material for constructing artificial molecular structures and strategy which has excellent intrinsic characteristics, including programmability, self-organization, molecular recognition, and molecular-scale structuring properties, makes it an attractive nanoscale building material. Excitingly, DNA can be considered as a natural candidate for molecular self-assembly. In this review, we have focused on the methods for DNA self assembling patterns within the molecular fabric of DNA lattices.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Eshaghian-Wilner M (ed) (2009) Inspired and nanoscale integrated computing. Wiley, New York

    Google Scholar 

  2. LaBean TH, Winfree E, Reif JH (1999) Discrete Math Theoret Comput Sci 54:123

    MathSciNet  Google Scholar 

  3. Jonoska N, Rozenberg G (eds) (2006) Nanotechnology: science and computation. Springer, Berlin

    MATH  Google Scholar 

  4. Seeman NC (2004) Sci Am 290:64

    Article  CAS  PubMed  Google Scholar 

  5. Seeman NC (1982) J Theor Biol 99:237

    Article  CAS  PubMed  Google Scholar 

  6. Kallenbach NR, Ma RI, Seeman NC (1983) Nature 305:829

    Article  CAS  ADS  Google Scholar 

  7. Seeman NC, Wang H, Yang X, Liu F, Mao C, Sun W, Wenzler L, Shen Z, Sha R, Yan H, Wong MH, Ardyen PS, Liu B, Qiu H, Li X, Qi J, Du SM, Zhang Y, Mueller JE, Fu TJ, Wang Y, Chen J (1998) Nanotechnology 9:257

    Article  CAS  ADS  Google Scholar 

  8. Mao C, Sun W, Seeman NC (1999) J Am Chem Soc 121:5437

    Article  CAS  Google Scholar 

  9. Fu TJ, Seeman NC (1993) Biochemistry 32:3211

    Article  CAS  PubMed  Google Scholar 

  10. Sha R, Liu F, Millar DP, Seeman NC (2000) Chem Biol 7:743

    Article  CAS  PubMed  Google Scholar 

  11. Mao C, Sun W, Shen Z, Seeman NC (1999) Nature 397:144

    Article  CAS  PubMed  ADS  Google Scholar 

  12. Liu F, Sha R, Seeman NC (1999) J Am Chem Soc 121:917

    Article  CAS  Google Scholar 

  13. Seeman NC (2001) Nano Lett 1:22

    Article  CAS  ADS  Google Scholar 

  14. Zhang X, Yan H, Shen Z, Seeman NC (2002) J Am Chem Soc 124:12940

    Article  CAS  PubMed  Google Scholar 

  15. Yan H, Park SH, Finkelstein G, Reif JH, LaBean TH (2003) Science 301:1882

    Article  CAS  PubMed  ADS  Google Scholar 

  16. Liao S, Seeman NC (2004) Science 306:2072

    Article  CAS  PubMed  ADS  Google Scholar 

  17. Yang X, Wenzler LA, Qi J, Li X, Seeman NC (1998) J Am Chem Soc 120(38):9779

    Article  CAS  Google Scholar 

  18. Mao C, LaBean TH, Reif JH, Seeman NC (2000) Nature 407:493

    Article  CAS  PubMed  ADS  Google Scholar 

  19. Ding BQ, Sha RJ, Seeman NC (2004) J Am Chem Soc 126:10230

    Article  CAS  PubMed  Google Scholar 

  20. Liu D, Wang M, Deng Z, Walulu R, Mao C (2004) J Am Chem Soc 126:2324

    Article  CAS  PubMed  Google Scholar 

  21. Reishus D, Shaw B, Brun Y, Chelyapov N, Adleman L (2005) J Am Chem Soc 127:17590

    Article  CAS  PubMed  Google Scholar 

  22. Ke Y, Liu Y, Zhang J, Yan H (2006) J Am Chem Soc 128:4414

    Article  CAS  PubMed  Google Scholar 

  23. Wei B, Mi Y (2005) Biomacromolecules 6:2528

    Article  CAS  PubMed  Google Scholar 

  24. Mathieu F, Liao S, Kopatsch J, Wang T, Mao C, Seeman NC (2005) Nano Lett 5:661

    Article  CAS  PubMed  ADS  Google Scholar 

  25. Li H, Carter JD, LaBean TH (2009) Mater Today 12:24

    Article  CAS  Google Scholar 

  26. Sharma J, Chhabra R, Cheng A, Brownell J, Liu Y, Yan H (2009) Science 323:112

    Article  CAS  PubMed  ADS  Google Scholar 

  27. LaBean TH (2009) ACS national meeting, Salt Lake City, Utah

  28. Simmel FC (2008) Angew Chem Int Ed 47:5884

    Article  CAS  Google Scholar 

  29. Le JD, Pinto Y, Seeman NC, Forsyth KM, Taton TA, Kiehl RA (2004) Nano Lett 4:2343

    Article  CAS  ADS  Google Scholar 

  30. Li H, Park SH, Reif JH, LaBean TH, Yan H (2004) J Am Chem Soc 126:418

    Article  CAS  PubMed  Google Scholar 

  31. Rinker S, Ke Y, Liu Y, Chhabra R, Yan H (2008) Nat Nanotechnol 3:418

    Article  CAS  PubMed  Google Scholar 

  32. Fruk L, Müller J, Weber G, Narváez A, Domínguez E, Niemeyer CM (2007) Chem Eur J 13:5223

    Article  CAS  Google Scholar 

  33. Weizmann Y, Braunschweig AB, Wilner OI, Cheglakov Z, Willner IA (2008) Proc Natl Acad Sci 105:5289

    Article  CAS  PubMed  ADS  Google Scholar 

  34. Diehl MR, Zhang K, Lee HJ, Tirrell DA (2006) Science 311:1468

    Article  CAS  PubMed  ADS  Google Scholar 

  35. Niemeyer CM, Koehler J, Wuerdemann C (2002) ChemBioChem 3:242

    Article  CAS  PubMed  Google Scholar 

  36. Wilner OI, Weizmann Y, Gill R, Lioubashevski O, Freeman R, Willner I (2009) Nat Nanotechnol 4:249

    Article  CAS  PubMed  ADS  Google Scholar 

  37. Abbaci A, Haliyo DS, Regnier S (2008) Second international conference on quantum, nano and micro technologies, Sainte Luce, Martinique, February

  38. Held GA, Grinstein G, Tu Y (2003) Proc Natl Acad Sci 100:7575

    Article  CAS  PubMed  ADS  Google Scholar 

  39. Chen YA, Chou CC, Lu X, Slate EH, Peck K, Xu W, Voit EO, Almeida JS (2006) BMC Bioinform 7:101

    Article  CAS  Google Scholar 

  40. Peterlinz KA, Georgiadis RM (1997) J Am Chem Soc 119:3401

    Article  CAS  Google Scholar 

  41. Gao Y, Wolf LK, Georgiadis RM (2006) Nucleic Acids Res 34:3370

    Article  CAS  PubMed  Google Scholar 

  42. Carlon E, Heim T (2006) Physica A 362:433

    Article  CAS  ADS  Google Scholar 

  43. Mirkin CA, Letsinger RL, Mucic RC, Storhoff JJ (1996) Nature 382:607

    Article  CAS  PubMed  ADS  Google Scholar 

  44. Strother T, Cai W, Zhao X, Hamers RJ, Smith LM (2000) J Am Chem Soc 122:1205

    Article  CAS  Google Scholar 

  45. Sieval AB, Demirel AL, Nissink JWM, Linford MR, Maas JH, de Jeu WH, Zuilhof H, Sudholter ERJ (1998) Langmuir 14:1759

    Article  CAS  Google Scholar 

  46. Linford MR, Fenter P, Eisenberger PM, Chidsey CED (1995) J Am Chem Soc 117:3145

    Article  CAS  Google Scholar 

  47. Turberfield AJ, Mitchell J, Yurke B, Mills APJ, Blakey M, Simmel F (2003) Phys Rev Lett 90:102

    Article  Google Scholar 

  48. Nuzzo RG, Allara DL (1983) J Am Chem Soc 105:4481

    Article  CAS  Google Scholar 

  49. Bain CD, Whitesides GM (1989) Angew Chem Int Ed 28:506

    Article  Google Scholar 

  50. Zhang YW, Seeman NC (1994) J Am Chem Soc 116:1661

    Article  CAS  Google Scholar 

  51. Hickman JJ, Laibinis PE, Auerbach DI, Zou C, Gardner TJ, Whitesides GM, Wrighton MS (1992) Langmuir 8:357

    Article  CAS  Google Scholar 

  52. Pathak S, Choi SK, Arnheim N, Thompson ME (2001) J Am Chem Soc 123:4103

    Article  CAS  PubMed  Google Scholar 

  53. Alivisatos AP, Johnsson KP, Peng X, Wilson TE, Loweth CJ, Bruchez MP, Schultz PG (1996) Nature 382:609

    Article  CAS  PubMed  ADS  Google Scholar 

  54. Niemeyer CM, Burger W, Peplies J (1998) Angew Chem Int Ed 37:2265

    Article  CAS  Google Scholar 

  55. Sun Y, Kiang CH (2005) Nanobiotechnology 2:224

    CAS  Google Scholar 

  56. Beaucage SL (ed) (2007) Current protocols in nucleic acid chemistry. Wiley, New York

    Google Scholar 

  57. Carell T, Behrens C, Gierlich J (2003) Biomol Chem 1:2221

    Article  CAS  Google Scholar 

  58. Kool ET (2002) Acc Chem Res 35:936

    Article  CAS  PubMed  Google Scholar 

  59. Tanaka K, Shionoya M (1999) J Org Chem 64:5002

    Article  CAS  Google Scholar 

  60. Atwell S, Meggers E, Spraggon G, Schultz PG (2001) J Am Chem Soc 123:12364

    Article  CAS  PubMed  Google Scholar 

  61. Wagenknecht HA (2003) Angew Chem Int Ed 42:3204

    Article  CAS  Google Scholar 

  62. Tanaka K, Tengeiji A, Kato T, Toyama N, Shionoya M (2003) Science 299:1212

    Article  CAS  PubMed  ADS  Google Scholar 

  63. Landweber LF, Baum EB (eds) (1999) DNA based computers II. American Mathematical Society, Rhode Island

    Google Scholar 

  64. Park SH, Pistol C, Ahn SJ, Reif JH, Lebeck AR, Dwyer C, LaBean TH (2006) Angew Chem Int Ed 45:735

    Article  CAS  Google Scholar 

  65. Chworos A, Severcan I, Koyfman A, Weinkam P, Oroudjev E, Hansma H, Jaeger L (2004) Science 6:2068

    Article  ADS  Google Scholar 

  66. Park SH, Yin P, Liu Y, Reif JH, LaBean TH, Yan H (2005) Nano Lett 5:729

    Article  CAS  PubMed  ADS  Google Scholar 

  67. Park SH, Finkelstein G, LaBean TH (2008) J Am Chem Soc 130:40

    Article  CAS  PubMed  Google Scholar 

  68. Fujibayashi K, Hariadi R, Park SH, Winfree E, Murata S (2008) Nano Lett 8:1791

    Article  CAS  PubMed  ADS  Google Scholar 

  69. Yin P, Hariadi RF, Sahu S, Choi HMT, Park SH, LaBean TH, Reif JH (2008) Science 321:824

    Article  CAS  PubMed  ADS  Google Scholar 

  70. Douglas SM, Dietzl H, Lied T, Högberg B, William FG, Shih M (2009) Nature 459:414

    Article  CAS  PubMed  ADS  Google Scholar 

  71. Winfree E, Liu FR, Wenzler LA, Seeman NC (1998) Nature 394:539

    Article  CAS  PubMed  ADS  Google Scholar 

  72. Rothemund PWK (2006) Nature 440:297

    Article  CAS  PubMed  ADS  Google Scholar 

  73. Chen JH, Seeman NC (1991) Nature 350:631

    Article  CAS  PubMed  ADS  Google Scholar 

  74. Shih WM, Quispe JD, Joyce GF (2004) Nature 427:618

    Article  CAS  PubMed  ADS  Google Scholar 

  75. Goodman RP, Schaap IAT, Tardin CF, Erben C, Berry RM, Schmidt CF, Turberfield AJ (2005) Science 310:1661

    Article  CAS  PubMed  ADS  Google Scholar 

  76. Goodman RP, Berry RM, Turberfield AJ (2004) Chem Commun 1372

  77. Douglas SM, Chou JJ, Shih WM (2007) Proc Natl Acad Sci 104:6644

    Article  CAS  PubMed  ADS  Google Scholar 

  78. He Y, Ye T, Su M, Zhang C, Ribbe AE, Jiang W, Mao C (2007) Nature 452:198

    Article  ADS  Google Scholar 

  79. Grainger DW (2009) Nat Nanotechnol 4:543

    Article  CAS  PubMed  ADS  Google Scholar 

  80. Goodman RP, Heilemann M, Doose SR, Erben CM, Kapanidis AN, Turberfield AJ (2008) Nat Nanotechnol 3:93

    Article  CAS  PubMed  ADS  Google Scholar 

  81. Zhang Z, Fan C, He L (2005) Curr Nanosci 1:89

    Article  CAS  ADS  Google Scholar 

  82. LaBean TH, Yan H, Kopatsch J, Liu F, Winfree E, Reif JH, Seeman NC (2000) J Am Chem Soc 122:1848

    Article  CAS  Google Scholar 

  83. Wilner OI, Shimron S, Weizmann Y, Wang ZG, Willner I (2009) Nano Lett 9:2040

    Article  CAS  PubMed  ADS  Google Scholar 

  84. Wang ZG, Wilner OI, Willner I (2009) Nano Lett 9:4098

    Article  CAS  PubMed  ADS  Google Scholar 

  85. Shin JS, Niles Pierce A (2004) J Am Chem Soc 126:10834

    Article  CAS  PubMed  Google Scholar 

  86. Yin P, Yan H, Daniel XG, Turberfield AJ, Reif JH (2004) Angew Chem Int Ed 43:4906

    Article  CAS  Google Scholar 

  87. Kershner RJ, Bozano LD, Micheel CM, Hung AM, Fornof AR, Cha JN, Rettner CT, Bersani M, Frommer J, Rothemund PWK, Wallraff GM (2009) Nat Nanotechnol 4:557

    Article  CAS  PubMed  ADS  Google Scholar 

  88. Deng Z, Mao C (2004) Angew Chem Int Ed 43:4068

    Article  CAS  Google Scholar 

  89. Benenson Y, Elizur TP, Adar R, Keinan E, Livneh Z, Shapiro E (2001) Nature 414:430

    Article  CAS  PubMed  ADS  Google Scholar 

  90. Green SJ, Lubrich D, Turberfield AJ (2006) J Biophys 91:2966

    Article  CAS  Google Scholar 

  91. Venkataraman S, Dirks RM, Rothemund PWK, Winfree E, Pierce NA (2007) Nat Nanotechnol 2:490

    Article  PubMed  Google Scholar 

  92. Keren K, Berman RS, Buchstab E, Sivan U, Braun E (2003) Science 302:1380

    Article  CAS  PubMed  ADS  Google Scholar 

Download references

Acknowledgement

This work was supported by Kyungwon University Research Fund in 2009.

Author information

Authors and Affiliations

  1. College of Bionanotechnology, Kyungwon University, Gyeonggi-Do, 461701, South Korea

    Sathya Sadhasivam & Kyu Sik Yun

Authors
  1. Sathya Sadhasivam
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kyu Sik Yun
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Kyu Sik Yun.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sadhasivam, S., Yun, K.S. DNA self-assembly: prospectus and its future application. J Mater Sci 45, 2543–2552 (2010). https://doi.org/10.1007/s10853-010-4237-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10853-010-4237-6

Keywords

Search

Navigation