Abstract
Objectives
To assess the effectiveness of colposcopy in detecting cervical lesions and to grade them according to Reid score and Swede score, and compare it with histopathology results.
Methods
This study was conducted on 130 patients in a tertiary care centre, who were subjected to pap smear and colposcopy. The cervical lesions were graded according to Reid score and Swede score, and a biopsy was obtained from the lesion. Histopathology results were correlated with colposcopy findings, and the scores were compared.
Results
The colposcopic findings using Reid score and Swede score correlated with histopathology results in the study population. The association between colposcopic impression and histopathology result was highly significant (p < 0.001), using both Reid score and Swede score. The sensitivity, specificity, PPV and NPV of Reid score (overall) was 86.2%, 80.20%, 55.56% and 95.3%, respectively. The diagnostic accuracy was 81.54%. At score > 5, specificity increased to 99% and diagnostic accuracy was 92.31%. The overall sensitivity, specificity, PPV, NPV and diagnostic accuracy of Swede score was 89.7%, 49.5%, 33.8%, 94.3% and 48.46%, respectively. As the cut off value increased, the sensitivity decreased. But the specificity, PPV, NPV and diagnostic accuracy increased and was statistically significant. The specificity and PPV was 100% at score > 8.
Conclusion
As the cut off value increased, the diagnostic accuracy of both the Scores increased, and was more accurate in detecting high-grade lesions.
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Funding
This study was funded by Father Mullers Research Centre.
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AS: protocol development, data collection, data analysis, manuscript writing, Manuscript editing. DK V:protocol development, data analysis, manuscript editing. PD: manuscript editing.
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The authors declare that they have no conflict of interest.
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Approval was obtained from the ethics committee of Father Muller Research Centre. The procedures used in this study adhere to the tenets of the Declaration of Helsinki.
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Written informed consent was taken from all the individual participants included in the study.
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Safoorah, A., Kanagal, D. & D’Cunha, P. Colposcopic analysis of cervical lesions using popular scoring systems: Reid versus Swede. Arch Gynecol Obstet 304, 1253–1258 (2021). https://doi.org/10.1007/s00404-021-06184-7
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DOI: https://doi.org/10.1007/s00404-021-06184-7