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Körperliche Aktivität und kardiovaskuläre Erkrankungen

Physical activity and cardiovascular disease

  • Leitthema
  • Published:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Aims and scope

Zusammenfassung

Erkrankungen des Herz-Kreislauf-Systems sind für ungefähr 50% der Todesfälle in den westlichen Industrienationen verantwortlich. Körperliche Inaktivität gilt als ein bedeutsamer kardiovaskulärer Risikofaktor. Die vorliegende Arbeit gibt einen Überblick über die aktuellen Studien, die sich mit dem Stellenwert mangelnder körperlicher Aktivität als Risikofaktor für das Auftreten kardiovaskulärer Erkrankungen befassen. Dabei wird auch darauf eingegangen, wie Umfang und Intensität der körperlichen Aktivität, das Alter, der späte Beginn der körperlichen Aktivität und der Body-Mass-Index den Zusammenhang zwischen körperlicher Aktivität und kardiovaskulären Erkrankungen beeinflussen.

Abstract

Cardiovascular disease is the leading cause of mortality in western industrialized countries. Physical inactivity is known to be an important risk factor. The present publication gives an overview of studies with the topic physical activity and relative risk of cardiovascular disease. Furthermore, aspects influencing the association between physical activity and cardiovascular disease, e.g., the duration and intensity of exercise, adults older than 60 years, late onset of physical activity, and body mass index, are discussed.

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Literatur

  1. Lloyd-Jones D, Adams R, Carnethon M et al (2009) Heart disease and stroke statistics – 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 119(3):480–486

    Article  PubMed  Google Scholar 

  2. Shiroma EJ, Lee IM (2010) Physical activity and cardiovascular health: lessons learned from epidemiological studies across age, gender, and race/ethnicity. Circulation 122(7):743–752

    Article  PubMed  Google Scholar 

  3. Kokkinos P, Myers J (2010) Exercise and physical activity: clinical outcomes and applications. Circulation 122(16):1637–1648

    Article  PubMed  Google Scholar 

  4. Morris JN, Heady JA, Raffle PA et al (1953) Coronary heart-disease and physical activity of work. Lancet 265(6796):1111–1120

    Article  PubMed  CAS  Google Scholar 

  5. Nocon M, Hiemann T, Muller-Riemenschneider F et al (2008) Association of physical activity with all-cause and cardiovascular mortality: a systematic review and meta-analysis. Eur J Cardiovasc Prev Rehabil 15(3):239–246

    Article  PubMed  Google Scholar 

  6. Sofi F, Capalbo A, Cesari F et al (2008) Physical activity during leisure time and primary prevention of coronary heart disease: an updated meta-analysis of cohort studies. Eur J Cardiovasc Prev Rehabil 15(3):247–257

    Article  PubMed  Google Scholar 

  7. Fletcher GF, Blair SN, Blumenthal J et al (1992) Statement on exercise. Benefits and recommendations for physical activity programs for all Americans. A statement for health professionals by the committee on exercise and cardiac rehabilitation of the council on clinical cardiology, American Heart Association. Circulation 86(1):340–344

    PubMed  CAS  Google Scholar 

  8. Gohlke H, Albus C, Gysan DB et al (2009) Cardiovascular prevention in clinical practice (ESC and German guidelines 2007). Herz 34(1):4–14

    Article  PubMed  Google Scholar 

  9. Graham I, Atar D, Borch-Johnsen K et al (2007) European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth joint task force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts). Eur J Cardiovasc Prev Rehabil 14(Suppl 2):S1–S113

    Article  PubMed  Google Scholar 

  10. Mora S, Cook N, Buring JE et al (2007) Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms. Circulation 116(19):2110–2118

    Article  PubMed  CAS  Google Scholar 

  11. Smith TC, Wingard DL, Smith B et al (2007) Walking decreased risk of cardiovascular disease mortality in older adults with diabetes. J Clin Epidemiol 60(3):309–317

    Article  PubMed  Google Scholar 

  12. Stamatakis E, Hamer M, Lawlor DA (2009) Physical activity, mortality, and cardiovascular disease: Is domestic physical activity beneficial? The Scottish Health Survey – 1995, 1998, and 2003. Am J Epidemiol 169(10):1191–1200

    Article  PubMed  Google Scholar 

  13. Dam RM van, Li T, Spiegelman D et al (2008) Combined impact of lifestyle factors on mortality: prospective cohort study in US women. BMJ 337:a1440

    Article  PubMed  Google Scholar 

  14. Sesso HD, Paffenbarger RS Jr, Lee IM (2000) Physical activity and coronary heart disease in men: The Harvard Alumni Health Study. Circulation 102(9):975–980

    PubMed  CAS  Google Scholar 

  15. Manson JE, Greenland P, LaCroix AZ et al (2002) Walking compared with vigorous exercise for the prevention of cardiovascular events in women. N Engl J Med 347(10):716–725

    Article  PubMed  Google Scholar 

  16. Troiano RP, Berrigan D, Dodd KW et al (2008) Physical activity in the United States measured by accelerometer. Med Sci Sports Exerc 40(1):181–188

    PubMed  Google Scholar 

  17. Folsom AR, Arnett DK, Hutchinson RG et al (1997) Physical activity and incidence of coronary heart disease in middle-aged women and men. Med Sci Sports Exerc 29(7):901–909

    PubMed  CAS  Google Scholar 

  18. Carnethon MR (2009) Physical activity and cardiovascular disease: How much is enough? Am J Lifestyle Med 3(1 Suppl):44S–49S

    Article  PubMed  Google Scholar 

  19. Haskell WL, Lee IM, Pate RR et al (2007) Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation 116(9):1081–1093

    Article  PubMed  Google Scholar 

  20. Paffenbarger RS Jr, Hyde RT, Wing AL et al (1993) The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. N Engl J Med 328(8):538–545

    Article  PubMed  Google Scholar 

  21. Lee IM, Sesso HD, Paffenbarger RS Jr (2000) Physical activity and coronary heart disease risk in men: Does the duration of exercise episodes predict risk? Circulation 102(9):981–986

    PubMed  CAS  Google Scholar 

  22. Haskell WL, Lee IM, Pate RR et al (2007) Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation 116(9):1081–1093

    Article  PubMed  Google Scholar 

  23. Nelson ME, Rejeski WJ, Blair SN et al (2007) Physical activity and public health in older adults: recommendation from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc 39(8):1435–1445

    Article  PubMed  Google Scholar 

  24. Li TY, Rana JS, Manson JE et al (2006) Obesity as compared with physical activity in predicting risk of coronary heart disease in women. Circulation 113(4):499–506

    Article  PubMed  Google Scholar 

  25. Tanasescu M, Leitzmann MF, Rimm EB et al (2002) Exercise type and intensity in relation to coronary heart disease in men. JAMA 288(16):1994–2000

    Article  PubMed  Google Scholar 

  26. Hamer M, Chida Y (2008) Walking and primary prevention: a meta-analysis of prospective cohort studies. Br J Sports Med 42(4):238–243

    Article  PubMed  CAS  Google Scholar 

  27. Caspersen CJ, Powell KE, Christenson GM (1985) Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep 100(2):126–131

    PubMed  CAS  Google Scholar 

  28. Myers J, Prakash M, Froelicher V et al (2002) Exercise capacity and mortality among men referred for exercise testing. N Engl J Med 346(11):793–801

    Article  PubMed  Google Scholar 

  29. Berry JD, Willis B, Gupta S et al (2011) Lifetime risks for cardiovascular disease mortality by cardiorespiratory fitness levels measured at ages 45, 55, and 65 years in men. The Cooper Center Longitudinal Study. J Am Coll Cardiol 57(15):1604–1610

    Article  PubMed  Google Scholar 

  30. Blair SN, Cheng Y, Holder JS (2001) Is physical activity or physical fitness more important in defining health benefits? Med Sci Sports Exerc 33(6 Suppl):S379–S399

    Article  PubMed  CAS  Google Scholar 

  31. Williams PT (2001) Physical fitness and activity as separate heart disease risk factors: a meta-analysis. Med Sci Sports Exerc 33(5):754–761

    PubMed  CAS  Google Scholar 

  32. Fogelholm M (2010) Physical activity, fitness and fatness: relations to mortality, morbidity and disease risk factors. A systematic review. Obes Rev 11(3):202–221

    Article  PubMed  CAS  Google Scholar 

  33. Lee DC, Sui X, Blair SN (2009) Does physical activity ameliorate the health hazards of obesity? Br J Sports Med 43(1):49–51

    Article  PubMed  CAS  Google Scholar 

  34. Sui X, LaMonte MJ, Laditka JN et al (2007) Cardiorespiratory fitness and adiposity as mortality predictors in older adults. JAMA 298(21):2507–2516

    Article  PubMed  CAS  Google Scholar 

  35. Bouchard C, Rankinen T (2001) Individual differences in response to regular physical activity. Med Sci Sports Exerc 3(6 Suppl):S446–S451

    Google Scholar 

  36. Skinner JS, Jaskolski A, Jaskolska A et al (2001) Age, sex, race, initial fitness, and response to training: the HERITAGE Family Study. J Appl Physiol 90(5):1770–1776

    PubMed  CAS  Google Scholar 

  37. Joyner MJ, Green DJ (2009) Exercise protects the cardiovascular system: effects beyond traditional risk factors. J Physiol 587(Pt 23):5551–5558

    Article  PubMed  CAS  Google Scholar 

  38. Green DJ, O’Driscoll G, Joyner MJ et al (2008) Exercise and cardiovascular risk reduction: time to update the rationale for exercise? J Appl Physiol 105(2):766–768

    Article  PubMed  Google Scholar 

  39. Thijssen DH, Maiorana AJ, O’Driscoll G et al (2010) Impact of inactivity and exercise on the vasculature in humans. Eur J Appl Physiol 108(5):845–875

    Article  PubMed  Google Scholar 

  40. Green DJ, Spence A, Halliwill JR et al (2011) Exercise and vascular adaptation in asymptomatic humans. Exp Physiol 96(2):57–70

    PubMed  Google Scholar 

  41. Green DJ, Maiorana A, O’Driscoll G et al (2004) Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol 561(Pt 1):1–25

    Article  PubMed  CAS  Google Scholar 

  42. Hambrecht R, Adams V, Erbs S et al (2003) Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation 107(25):3152–3158

    Article  PubMed  CAS  Google Scholar 

  43. Laughlin MH, Newcomer SC, Bender SB (2008) Importance of hemodynamic forces as signals for exercise-induced changes in endothelial cell phenotype. J Appl Physiol 104(3):588–600

    Article  PubMed  Google Scholar 

  44. Monahan KD, Dinenno FA, Tanaka H et al (2000) Regular aerobic exercise modulates age-associated declines in cardiovagal baroreflex sensitivity in healthy men. J Physiol 529(Pt 1):263–271

    Article  PubMed  CAS  Google Scholar 

  45. Rennie KL, Hemingway H, Kumari M et al (2003) Effects of moderate and vigorous physical activity on heart rate variability in a British study of civil servants. Am J Epidemiol 158(2):135–143

    Article  PubMed  Google Scholar 

  46. Sugawara J, Komine H, Hayashi K et al (2007) Systemic alpha-adrenergic and nitric oxide inhibition on basal limb blood flow: effects of endurance training in middle-aged and older adults. Am J Physiol Heart Circ Physiol 293(3):H1466–H1472

    Article  PubMed  CAS  Google Scholar 

  47. Byberg L, Melhus H, Gedeborg R et al (2009) Total mortality after changes in leisure time physical activity in 50 year old men: 35 year follow-up of population based cohort. BMJ 338:b688

    Article  PubMed  Google Scholar 

  48. Albert CM, Mittleman MA, Chae CU et al (2000) Triggering of sudden death from cardiac causes by vigorous exertion. N Engl J Med 343(19):1355–1361

    Article  PubMed  CAS  Google Scholar 

  49. Chevalier L, Hajjar M, Douard H et al (2009) Sports-related acute cardiovascular events in a general population: a French prospective study. Eur J Cardiovasc Prev Rehabil 16(3):365–370

    Article  PubMed  Google Scholar 

  50. Teeffelen WM van, de Beus MF, Mosterd A et al (2009) Risk factors for exercise-related acute cardiac events. A case-control study. Br J Sports Med 43(9):722–725

    Article  PubMed  Google Scholar 

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Hansel, J., Burgstahler, C. & Nieß, A. Körperliche Aktivität und kardiovaskuläre Erkrankungen. Bundesgesundheitsbl. 55, 17–23 (2012). https://doi.org/10.1007/s00103-011-1390-2

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