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DBU(OAc)–TBAB-Mediated One-Pot Three-component Synthesis of 1H-Imidazol-5(4H)-one Derivatives

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Abstract

One-pot three-component synthesis of 1H-imidazol-5(4H)-one derivatives from (Z)-4-(aryl­methylidene)-2-methyl-1,3-oxazol-5(4H)-one, methylamine, and N-benzylideneaniline has been developed using DBU (OAc) as an ionic liquid catalyst and TBAB as promoter. The reactions were carried out on heating at 75–80°C for 25–30 min to afford (4Z)-4-(arylmethylidene)-1-methyl-2-(2-phenylethenyl)-1H-imidazol-5(4H)-one derivatives in good yields.

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ACKNOWLEDGMENTS

The authors are thankful to the authorities of Department of Chemistry, Institute of Aeronautical Engineering, Dundigal, Hyderabad, for providing laboratory facilities.

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Authors and Affiliations

  1. Department of Chemistry, Institute of Aeronautical Engineering, Dundigal, 500043, Hyderabad, India

    V. A. Rani

  2. Department of Chemistry, Jawaharlal Nehru Technological University, 500085, Hyderabad, India

    Y. B. Kumari

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  1. V. A. Rani
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  2. Y. B. Kumari
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Correspondence to V. A. Rani.

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Rani, V.A., Kumari, Y.B. DBU(OAc)–TBAB-Mediated One-Pot Three-component Synthesis of 1H-Imidazol-5(4H)-one Derivatives. Russ J Org Chem 58, 352–355 (2022). https://doi.org/10.1134/S1070428022030125

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