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Hyperbaric Oxygen Therapy in Orthopaedics: An Adjunct Therapy with an Emerging Role

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Abstract

Introduction

Hyperbaric oxygen therapy (HBOT) has emerged as an adjunct treatment modality in various orthopedic and rheumatological conditions. Undersea and Hyperbaric Medical Society (UHMS) defined the minimum number of HBOT cycles, dose, and frequency for various diseases. UHMS laid the 14 absolute indications for HBOT. This article deals with the mechanism of actions of HBOT and evidence of various musculoskeletal disorders where HBOT was utilized to accelerate the healing process of the diseases.

Materials and methods

The review literature search was conducted by using PubMed, SCOPUS, and other database of medical journals for identifying, reviewing, and evaluating the published clinical trial data, research study, and review articles for the use of HBOT in musculoskeletal disorders.

Results

Various clinical researchers documented cellular and biochemical advantages of HBOT which possess allodynic effects, anti-inflammatory, and prooxygenatory effects in patients with musculoskeletal conditions. Studies on the usage of HBOT in avascular necrosis and wound healing provide a platform for exploring the plausible uses of HBOT in other musculoskeletal conditions. Literature evidence states the complications associated with HBOT therapy.

Conclusion

The existing HBOT protocols have to be optimized for various musculoskeletal disorders. Large scale blinded RCTs have to be performed for demonstrating the level of evidence in the usage of HBOT in various musculoskeletal clinical scenarios.

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Authors and Affiliations

  1. Department of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Chennai, Tamil Nadu, 600056, India

    Madhan Jeyaraman

  2. South Texas Orthopaedic Research Institute (STORI Inc.), Laredo, TX, 78045, USA

    Madhan Jeyaraman

  3. Department of Orthopaedics, Atal Bihari Vajpayee Institute of Medical Sciences, Dr Ram Manohar Lohia Hospital, New Delhi, 110001, India

    Abdus Sami & Vijay Kumar Jain

  4. Department of Orthopaedics, All India Institute of Medical Sciences, Bhubaneswar, Odisha, 751019, India

    Arulkumar Nallakumarasamy

  5. Department of Orthopaedics, Rathimed Specialty Hospital, Chennai, Tamil Nadu, 600040, India

    Naveen Jeyaraman

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Jeyaraman, M., Sami, A., Nallakumarasamy, A. et al. Hyperbaric Oxygen Therapy in Orthopaedics: An Adjunct Therapy with an Emerging Role. JOIO 57, 748–761 (2023). https://doi.org/10.1007/s43465-023-00837-2

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