Abstract
Hydrothermal vapor treatment method was applied for preparation of ceramic biomaterials. Hydroxyapatite (Ca10(PO4)6(OH)2; HA) ceramics prepared by sintering with random crystal surface have already been used as bone-repairing materials which can directly bond to natural bones. If materials of HA could have the tailored specific crystal surface, they should have the advantage of adsorptive activity and osteoconductivity in comparison with the sintered HA. In the present study, porous HA sheets of about 50 μm to 1 mm in thickness and porous HA granules of about 50 μm to 1 mm in size with tailored crystal surface were prepared by the hydrothermal vapor exposure method at temperatures below 200°C. Porous sheets and porous granules of HA with controlled crystal surface should be suitable for scaffold of cultured bone, for bone graft material and for drug delivery system (DDS).
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H. OHGUSHI AND A. I. CAPLAN, J. Biomed. Mater. Res. (Applied Biomaterials) 48 (1999) 913.
K. IOKU, M. YOSHIMURA AND S. SOMIYA, in “Bioceramics 1 ” (Ishiyaku EuroAmerica, Tokyo and St. Louis, 1989) p. 62.
K. IOKU, M. YOSHIMURA AND S. SOMIYA idem., Biomaterials, 11 (1990) 57.
K. IOKU, M. YOSHIMURA AND S. SOMIYA idem., Phosphorus Res. Bull., 1 (1991) 15.
M. YOSHIMURA, H. SUDA, K. OKAMOTO AND K. IOKU, J. Mater. Sci. 29 (1994) 3399.
K. IOKU, K. YAMAMOTO, K. YANAGISAWA AND N. YAMASAKI, Phosphorus Res. Bull. 4 (1994) 65.
K. IOKU, A. OSHITA, H. FUJIMORI, S. GOTO AND M. YOSHIMURA, Trans. Mater. Res. Soc. Japan 26 (2001) 1243.
K. IOKU, S. YAMAUCHI, H. FUJIMORI, S. GOTO AND M. YOSHIMURA, Solid State Ionics 151 (2002) 147.
K. IOKU, S. NISHIMURA, Y. EGUCHI AND S. GOTO, Rev. High Pressure Sci. Technol. 7 (1998) 1398.
K. IOKU, M. FUKUHARA, H. FUJIMORI AND S. GOTO, Korean J. Ceram. 5 (1999) 115.
K. IOKU, H. MISUMI, H. FUJIMORI, S. GOTO AND M. YOSHIMURA, in Proc. 5th Int. Conf. Solvo-Thermal Reactions, NJ, USA, July 2002, edited by R. E. Riman (Rutgers, The State Univ. of NJ, USA, 2002), p. 233.
K. IOKU, M. TODA, H. FUJIMORI, S. GOTO AND M. YOSHIMURA, Key Engineering Materials 254–256 (2004) 19.
E. TENGROTENHUIS, W. J. M. VAN DER KEMP, J.G. BLOK, J.C. VAN MILTENBURG AND J. P. VAN DEREERDEN, Colloids and Surfaces B. Biointerfaces 6 (1996) 209.
H. MONMA AND T. KANAZAWA, J. Ceram. Soc. Japan 84 (1976) 209.
K. IOKU, T. MURAKAMI, Y. IKUMA AND M. YOSHIMURA, J. Ceram. Soc. Japan Int. Edition 100 (1992) 1015.
K. ISHIKAWA, P. DUCHEYNE AND S. RADIN, J. Mater. Sci.: Mater. Med. 4 (1993) 165.
W. PAUL AND C. P. SHARMA, ibid. J. Mater. Sci.: Mater. Med. 10 (1999) 383.
V. S. KOMLEV AND S. M. BARINOV, ibid. J. Mater. Sci.: Mater. Med. 13 (2002) 295.
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Ioku, K., Kawachi, G., Sasaki, S. et al. Hydrothermal preparation of tailored hydroxyapatite. J Mater Sci 41, 1341–1344 (2006). https://doi.org/10.1007/s10853-006-7338-5
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DOI: https://doi.org/10.1007/s10853-006-7338-5