Abstract
From 1975 through 1985, nine patients with a local recurrent lesion (LRL) of breast cancer to the skin flap of the chest wall were treated. Four had undergone primary mastectomies in our clinic and the other five were referred from other surgeons, following signs of recurrence. Aggressive topical therapy, such as resection or irradiation, proved effective in eradicating the LRL in all cases, thereby indicating that topical therapy is useful for improving quality of life. Adjuvant systemic chemo-immunoendocrine therapy is also required for patients with LRL, to increase longevity. Seven of the patients died of a distant metastasis within 66 months after the onset of LRL.
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References
Haagensen CD. In: Disease of the Breast. London: WB Saunders 1956; 636–644.
Bruce J, Carter DC, Fraser J. Patterns of recurrent disease in breast cancer. Lancet 1970; 1: 433–435.
Kusama S. Gann to Jikangaku. Gann no Rinshoh 1981; 27: 793–799. (in Japanese)
Gilliland MD, Barton RM, Copeland EM. The implications of local recurrence of breast cancer as the first site of therapeutic failure. Ann Surg 1983; 197: 284–287.
Auchincloss H. The nature of local recurrence following radical mastectomy. Cancer 1958; 11: 611–619.
Bonadonna G. In Cancer investigation and Management. Vol. 1. Breast cancer: Diagnostic and Management. New York: John Wiley and Sons, Chichester. 1981; 265.
Fritze D, Becher R, Massner B, Kaufman M, Bruntsch U, Gallmeiner WM, Mayer AC, Frings P, Abel U, Edler L, Jungi WF, Queisser W, Senn HJ. A randamized study of combination chemotherapy (VAC-FMC) with or without immunostimulation by Corynebacterium Parvum in metastatic breast cancen. Klin Wochenschr 1982; 60: 593–598.
Howell A, Barnes DM, Harland RNL, Redford J, Bramwell VHC, Wilkinson MJS, Swindell R, Crowther D, Sellwood RA. Steroid-hormone receptors and survivals after first relapse in breast cancer. Lancet 1984; 1: 588–591.
Poweles TJ, Ashley S, Ford HT, Gazet JC, Nash AG, Neville AM, Coombs AM Treatment of disseminated breast cancer with tamoxifen, aminogluthetimide, hydrocortisone, and donasol used in combination or sequentially. Lancet 1984; 1: 1369–1372.
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Naruse, T., Koike, A., Miyashita, A. et al. Local recurrence of breast cancer: Treatment of nine patients with a recurrence in the skin flap of the chest wall. The Japanese Journal of Surgery 17, 78–82 (1987). https://doi.org/10.1007/BF02470645
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DOI: https://doi.org/10.1007/BF02470645