Preoperative risk factors for deep vein thrombosis in patients with long bone fractures of lower extremityChinese Full Text
GUO Yu-xiang;ZHAO Qing-hua;LIN Fu-qin;CAI Xiao-lin;YING Xiao-feng;LIN Lu-pan;ZOU Rui;XIANG Chun-lin;WEN Chuan-yang;JIANG Qing;Department of Orthopaedic Trauma, Luhe Hospital Affiliated to Medical School of Yangzhou University;
Abstract: Objective To investigate the preoperative risk factors for deep vein thrombosis（DVT） in patients with long bone fracture of lower extremity. Methods The clinical data were collected of patients who had been treated in our department for long bone fractures of lower extremity between June 2011 and February 2014. DVT was detected by direct multi-slice spiral CT venography. The patients were divided into DVT-free group and DVT group. A binary logistic regression was performed,using age, sex, associated injury, associated systemic disease, fracture type, preoperative traction and immobilization,preoperative prophylactic measures against DVT, and D-Dimer level were taken as independent variables and occurrence of preoperative DVT as the dependent variable. The Chi-square test and Multivariate Logistic regression were used to examine the relationship between these factors and to pick out the risk factors for DVT. Results DVT occurred at the lower extremity was 47（34.8%） of 135 patients. Of which, 1 case was mixed type, 3 cases were central type, and the others were peripheral type. Associated injury, associated systemic disease, and absence of prophylactic measures against DVT were found to be the risk factors associated with DVT（P ＜0.05）. Logistic regression analysis showed that associated injury [OR =3.644, 95% CI（1.616, 8.216）, P =0.002], associated systemic disease [OR =2.819, 95% CI（1.062, 7.487）, P =0.038], and absence of preoperative prophylaxis [OR =0.382, 95% CI（0.175, 0.836）, P =0.016] were independent risk factors associated with DVT before surgery. Conclusion Among patients with long bone fractures of lower extremity, associated injury, associated systemic diseases, and absence of prophylactic measures against DVT are independent risk factors contributing to DVT before surgery. Prophylactic measures against DVT. Consequently, close monitoring and preoperative prophylaxis should be taken in trauma patients to prevent the DVT.
Keywords：
Deep vein thrombosis; Long bone fracture of lower extremity; Preoperative; Risk factor; Logistic regression analysis;
- Series：
(E) Medicine ＆ Public Health
- Subject：
Surgery
- Classification Code：
R687.3
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