[关键词]
[摘要]
莪术醇作为莪术Curcuma rhizoma的重要成分,具有抗病毒、抗炎、抗肿瘤等药理活性,在抗肿瘤研究领域受到了广泛关注。通过查阅近年来国内外相关文献,综述了莪术醇的天然来源、抗肿瘤作用机制及其结构修饰、抗肿瘤活性评价等方面的研究进展,为其进一步的结构优化策略提供新的研究思路。
[Key word]
[Abstract]
Curcumol, as an important component of Curcuma Rhizoma, has anti-virus, anti-inflammatory, anti-tumor and other pharmacological activities, which has attracted more and more attentions in anti-tumor research area. The progress on the natural source, anti-tumor mechanism, structural modification, and anti-tumor evaluation of curcumol are reviewed in this paper, which will provide a novel strategy for its further structural optimization.
[中图分类号]
R282.71
[基金项目]
国家自然科学基金资助项目(21372203);浙江中医药大学省重点建设高校优势特色学科(中药学)开放基金资助项目(ZYAOXZD2019008);浙江省新苗人才计划项目(2019R403044)