FR191512, a Novel Anti-influenza Agent Isolated from a Fungus Strain No.17415 I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Structure Elucidation

YUTAKA NISHIHARA; EISAKU TSUJII; SFFIGEHIRO TAKASE; YASUHISA TSURUMI; TORU KINO; MOTOHIRO HINO; MICHIO YAMASHITA; SEUI HASHIMOTO

doi:10.7164/antibiotics.53.1333

FR191512, a Novel Anti-influenza Agent Isolated from a Fungus Strain No.17415

I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Structure Elucidation

YUTAKA NISHIHARA, EISAKU TSUJII, SFFIGEHIRO TAKASE, YASUHISA TSURUMI, TORU KINO, MOTOHIRO HINO, MICHIO YAMASHITA, SEUI HASHIMOTO

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JOURNAL FREE ACCESS

2000 Volume 53 Issue 12 Pages 1333-1340

DOI https://doi.org/10.7164/antibiotics.53.1333

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Abstract

In the course of our screening for anti-influenza agents of microbial origin, FR191512 was isolated from the cultured broth of fungus strain No.17415 as colorless powder. The structure of FR191512 was determined by several spectroscopic experiments as a novel polyphenolic compound. This compound showed potent antiviral activity against influenza A virus.

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