The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
Structure Determination of MS-444; a New Myosin Light Chain Kinase Inhibitor
YUMIKO AOTANIYUTAKA SAITOH
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1995 Volume 48 Issue 9 Pages 952-953

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Abstract

MS-444 is a novel myosin light chain kinase inhibitor, isolated from the culture broth of Micromonospora sp. KY7123. The structure of MS-444 was determined to be 5, 8-dihydroxy-3-methyl-(9H)-naphtho[2, 3-c]furan-4-one by means of spectral analysis.

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© Japan Antibiotics Research Association
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