2-ETHYL-5-(3-INDOLYL)OXAZOLE FROM STREPTOMYCES CINNAMOMEUS DISCOVERED BY CHEMICAL SCREENING
CHARACTERIZATION AND STRUCTURE ELUCIDATION BY X-RAY ANALYSIS
1982 Volume 35 Issue 5 Pages 549-555
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1982 Volume 35 Issue 5 Pages 549-555
In the lipophilic extracts from Streptomyces cinnamomeus 2-ethyl-5-(3-indolyl)oxazole (1a) was detected by chemical screening methods. The structure of the crystalline 1a was determined by spectroscopic and X-ray analysis. The new mono- and dibromo derivatives 1b and 1c are described. 1a is identical with pimprinethine and belongs to a group of microbial indolealkaloids, which can be regarded as masked tryptamine derivatives.
