MARIDOMYCIN, A NEW MACROLIDE ANTIBIOTIC. VII
INCORPORATION OF LABELED PRECURSORS INTO MARIDOMYCIN AND PREPARATION OF 14C-LABELED 9-PROPIONYLMARIDOMYCIN
1974 Volume 27 Issue 6 Pages 442-448
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1974 Volume 27 Issue 6 Pages 442-448
investigated by using Streptomyces hygroscopicus. Of some compounds, L-methionine-methyl- 14C was well incorporated into maridomycin molecule with 27% of the added radioactivity. Degradation studies of the labeled maridomycin revealed that one methyl group in aglycone, two methyl groups in mycaminose and one methyl group in mycarose were derived from the methyl group of L-methionine.
