The Production of Novel Sordarin Analogues by Biotransformation

RICHARD M. HALL; MICHAEL J. DAWSON; CAROL A. JONES; ANDREW D. ROBERTS; PHILIP J. SIDEBOTTOM; PAUL STEAD; NICK L. TAYLOR

doi:10.7164/antibiotics.54.948

RICHARD M. HALL, MICHAEL J. DAWSON, CAROL A. JONES, ANDREW D. ROBERTS, PHILIP J. SIDEBOTTOM, PAUL STEAD, NICK L. TAYLOR

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JOURNAL FREE ACCESS

2001 Volume 54 Issue 11 Pages 948-957

DOI https://doi.org/10.7164/antibiotics.54.948

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Abstract

The biotransformation of the fungal protein synthesis inhibitor sordarin is reported. Nine taxonomically diverse organisms supported the isolation and identification of twelve modified products. The structural diversity of the biotransformation products observed and their value in supporting further chemistry is discussed.

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