The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
OLIVANIC ACIDS, A FAMILY OF β-LACTAM ANTIBIOTICS WITH β-LACTAMASE INHIBITORY PROPERTIES PRODUCED BY STREPTOMYCES SPECIES
II. ISOLATION AND CHARACTERISATION OF THE OLIVANIC ACIDS MM 4550, MM 13902 AND MM 17880 FROM STREPTOMYCES OLIVACEUS
J. D. HOOD, S. J. BOX, M. S. VERRALL
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JOURNAL FREE ACCESS

1979 Volume 32 Issue 4 Pages 295-304

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Abstract

The olivanic acids MM 4550, MM 13902 and MM 17880 are members of a new family of β-lactam antibiotics. An isolation and purification process utilising ion-pair extraction and ion-exchange chromatography is described and the metabolites are characterized by physico-chemical and biological properties.

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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series A

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