A NEW ANTIBIOTIC, 1-(p-HYDROXYPHENYL)-2, 3-DIISOCYANO-4-(p-METHOXYPHENYL)-BUTA-1, 3-DIENE. II ELUCIDATION OF THE STRUCTURE (STUDIES ON ANTIVIRAL AND ANTITUMOR ANTIBIOTICS. III)

KUNIO ANDO; GAKUZO TAMURA; KEI ARIMA

doi:10.7164/antibiotics.21.587

The Journal of Antibiotics

Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820

A NEW ANTIBIOTIC, 1-(p-HYDROXYPHENYL)-2, 3-DIISOCYANO-4-(p-METHOXYPHENYL)-BUTA-1, 3-DIENE. II

ELUCIDATION OF THE STRUCTURE (STUDIES ON ANTIVIRAL AND ANTITUMOR ANTIBIOTICS. III)

KUNIO ANDO, GAKUZO TAMURA, KEI ARIMA

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JOURNAL FREE ACCESS

1968 Volume 21 Issue 10 Pages 587-591

DOI https://doi.org/10.7164/antibiotics.21.587

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Abstract

In our screening for antiviral antibiotics using the agar diffusion-plaque inhibition method, a new antibiotic was obtained in crystalline form from the filter cake of the fermented broth of Dichotomomyces albus SAITO. The structure of the antibiotic was determined to be l-(p-hydroxyphenyl)-2, 3-diisocyano-4 (p-methoxyphenyl)-buta-l, 3-diene from the interpretation of the ultraviolet absorption, infrared absorption, nuclear magnetic resonance and mass spectra.

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