This article describes the nursing experience of caring for a 21-year-old women with cholangioma. The duration of the nursing care was from Aug. 20 to Sept. 10 of 2018. Data were collected through direct nursing care, conversations, observation and physical evaluation; the assessment was reached by using the Gordon 11 functional health pattern for reference. The health problems identified included pain, nausea, vomiting, and anticipatory grief, which all prompted the author to investigate the issue of pain relief. Besides the analgesics, some adjuvant therapies, such as the therapeutic massage and music therapy, can decrease the intensity of pain. We also offered individualized nursing care, dietary education, breathing technique, acupoint massage, and oral hygiene care to attenuate the frequency of vomiting. To help the patient cope with the distressing mood, we evaluated the patient's physical status to see how likely she was able to fulfill her wishes, and then we helped her mother and friends to realize her wishes the best we could. We hope our presence and care had provided her with support and brought her hope and consolation. We hope the combination of nursing care, psychiatric care and disease control had helped alleviate the pain and suffering so the patient could live with dignity at the end of her life.