In this study, the foamed nickel photocatalyst filters coated with zinc oxide (ZnO) and ultraviolet (UV) light of 365 nm are equipped in the air cleaners. Air pollutants removal efficiency of the air cleaners are assessed in a closed chamber and the real sites. In the closed chamber, relative humidity (RH) is set at 70 ± 5 % as high RH and 40 ± 5 % as low RH; initial concentrations (IC) of formaldehyde (HCHO) are 0.5 ± 0.05 ppm as low IC and 1.0 ± 0.1 ppm as high IC; initial concentrations of total volatile organic compounds (TVOC) are 1.4 ± 0.1 ppm as low IC and 3.0 ± 0.3 ppm as high IC. Moreover, the removal efficiency in the air cleaner equipped with foamed nickel photocatalyst filters coated with titanium dioxide (TiO2) are assessed at the same conditions under UV light and are compared with that coated with ZnO. Furthermore, the nickel filters with higher removal efficiency are installed in the real sites and the indoor air quality are assessed. Finally, the environmental parameters of the chamber test are input to the mass balance model and airflow analysis software (CONTAM) to simulate the change of pollutant concentration with time at the real site. The mass balance model is validated by mean absolute percentage error (MAPE). Results of the 60-min chamber test for the ZnO filters show the highest removal efficiency for HCHO are under no UV light irradiation (7.88 % for low IC at low RH; 12.6 % for high IC at high RH; 11.45 % for low IC at high RH), while that for TVOC are under UV light irradiation (6.87 % for low IC at low RH; 15.75 % for high IC at high RH; 8.09 % for low IC at high RH). It also shows no matter under UV light irradiation or not, the highest removal efficiency for HCHO and TVOC are under high RH and IC. The removal efficiency of HCHO and TVOC by UV light are not significantly affected by IC and RH (4.25~5.89 % for HCHO and 3.33~5.11 % for TVOC). Clean air delivery rates (CADR) of the air cleaner are consistent with the air pollutant removal efficiency, i.e., higher CADR brings higher removal efficiency. The results show the removal efficiency of HCHO and TVOC by TiO2 photocatalyst filters are higher than which by ZnO photocatalyst filters under UV light irradiation. On the field test, air conditioners equipped with TiO2 photocatalyst filters were installed at the site. The MAPEs of the simulations are 13.52 % ~ 38.80 % for changes of HCHO concentrations in 20 min with mass balance model and airflow analysis software CONTAM, while the MAPEs the simulations are 8.28 %∼50.81 % for changes of TVOC concentrations. The MAPEs of HCHO and TVOC for CONTAM simulations are 5.38 % and 7.07 % , respectively, which shows the CONTAM has good accuracy. The removal efficiency of HCHO and TVOC were 0.09 ppm/day and 0.44 ppm/day, respectively.