背景:糖尿病預防為一全世界囑目之健康議題。為確認糖尿病高危險群,健康專家以空腹血糖或飯後血糖測試做為篩檢方式,然此兩者方式並不便利。因此,欲發展一簡單糖病前期篩檢工具,不須任何抽血 數據。 目的:本研究目的為發展一簡單篩檢糖尿病前期的工具。 方法:本研究為一社區為主之糖尿病前期篩檢。受試者主要來自南台灣一社區、一區域醫院及一醫學中心體檢部。共召募1112位受試者填寫問卷及參與空腹血糖測試。測試糖尿病前期篩檢工具的敏感性、特異性及準確性。 結果:糖尿病前期篩檢工具所包括預測因為年齡、吸菸狀態、腰圍、收縮壓、高血壓疾病與心血管疾病史。此篩檢工具分數範圍4-14分,最佳切點為4分,準確性AUC為.0.72(95%CI:0.69, 0.76),敏感性、特異性、陽性預測值、陰性預測值及分別為76.89%, 54.76%, 38.23%, 及86.68%。 結論:實證資料支持本研究發展之篩檢工具為一效度及可行性高篩檢工具,可廣泛使用於社區篩檢以早期確認無症狀之糖尿病前期者。
Background: Diabetes prevention is a global health issues. To identify people at high risk of developing the diabetes, the healthcare professionals have to measure fasting glucose or two-hour oral glucose tolerance test (OGTT) that is inconvenient, and costly. Thus, we attempt to develop a simple prediabetes screening tool (PST) without the laboratory data. Purpose: The purpose of this study is to develop and test a simple screening tool to identify people with pre-diabetes. Methods: We conducted a consecutive community-based prediabetes survey. The subjects recruited from the community and department of physical examination of one medical center and one metropolitan hospital in southern Taiwan. The subjects (N=1112) completed the questionnaire and underwent a fasting glucose test after their regular physical examination. The area under the receiver operating characteristic curve (AUC) was used in this study to examine the sensitivity and specificity of PST . Results: Risk factors comprised in the PST include age, smoking status, waist circumference, systolic blood pressure, hypertension, and history of cardiovascular disease. Scores for the screening tool ranged between 4 and 14 points. The area under the AUC was 0.72 (95%CI:0.69, 0.76) for the cutoff point of 4, the sensitivity , specificity, positive predictive value, and negative predictive value of the screening tool was 76.89%, 54.76%, 38.23%, and 86.68%, respectively. Conclusions: Empirical data supports the PST is a valid and feasible screening tool that could be widely used to early identify prediabetes people who may be asymptomatic in the community.