In our department, there was an electrical fire owing to a faulty instrument power cord causing combustion of a surgical cloth during endoscopic surgery. For Medical Personnel, the fire risk perception was 53.5% and the fire emergency response was only 71.3% before the program. We found that there was a lack of education related to operating room fires, with no standard operation procedure (SOP) for high-risk surgical fires, equipment had not been examined regularly and fire safety supplies were inadequate. The goals of the project were to provide a safe workplace for medical staff in the operating room, to improve response protocol for operating room fire prevention, and to protect both staff and patients. Resolution: The improvement program included 1). Setup SOP for high-risk operating room fire; 2). Conduct simulation-based learning; 3). Establish regulations for maintenance of equipment; 4). Design power protection devices; 5). Make gas cylinder holders; and 6). Add ＂fire evacuation kit＂ in the operating room. The improvement program introduced from May 2016 to April 2017 was effective. Both fire-risk perception and fire emergency response of healthcare personnel improved to 100% after the program.