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抗精神病藥物於老年人的使用

摘要


隨著人口結構日益老化,罹患神經退化性疾病如:失智症、老年憂鬱症或多重共病而伴隨的譫妄症患者與日俱增,老年人使用治療於精神症狀(激動、妄想、幻覺等)的抗精神病藥物(antipsychotic agent)機會也隨之上升。然而,老年人因藥物動力學(pharmacokinetics)及藥物效力學(pharmacodynamics)等原因,更容易產生副作用如:鎮靜、便秘、錐體外症候群、代謝症候群。因此,在老年人使用抗精神病藥物須更加謹慎。以下我們將就老人用藥安全與常見副作用、老年精神藥物動力與藥物效力學、抗精神病藥物相關對疾病治療原則做一一介紹。

參考文獻


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