Nursing is a professional business which deals with human life and health. We have to build standards to regulate and control the level of nursing (Chan, 1995). At medical intensive care unit (MICU) where the author works many patients have to spent a lot of time using indwelling catheters. According to the annual report at 1998, the ratio of patients using indwelling catheters is 91.58%, a very high ratio of catheter patients. Since our hospital has no standards for the care of indwelling catheter patients, nurses care for indwelling catheter in different ways, and the materials and the materials and cleaning results in caring for indwelling catheter patients are different. So standardizing skill are necessary steps that need to be executed immediately. This project aims to standardize the care of indwelling catheter patients, and make the materials less. Patients were more and comfort after receiving the care of indwelling catheter patients described below. The method included: (1) Collecting recent references, and deciding to using the soap and water as the process to clean for indwelling catheter. (2) Conducting an education of the care of indwelling catheter patients and publicity. (3) Coming to an understanding and definite model of the care of indwelling catheter patients. The results of this project have showed: We have not just unified the care of indwelling catheter patients but also decreased the costs. The material costs for the care of indwelling catheter patients in male patients has fallen to about 5.48N.T. dollars, and in female patients has fallen to about 8.39 N.T. dollars, The cleaning ratio is new 100% which before standardization was about 40%. These results prove that the project of standardization and contemporarization of care of patients with indwelling catheter is successful in improving the quality of nursing.