We use the CFDRC software to do the research about the valveless micropump which is driven by piezoelectrical materials and utilizes asymmetric obstacles to control the flow direction. For a micropump, it is crucial to find the optimal working frequency. When the working frequency is under 10K, swirls will arise nearby the obstacles. The phenomenon will lead the flow approach the wall and also affect the net flow about the swirl’s size. At high working frequency, the fluid-solid membrane may come out a peculiar mode, which is different from the first mode and the second mode. Besides, there might be a buffer zone while the two modes change, and it will cause the center of fluid-solid membrane drifting. Meanwhile, the result shows that a phase shift lagging when the excitation force exists in the vibration response.