The purposes of this study were to understand the status of religion among nursing students in Taiwan, and to explore the relationships between religion, spiritual health and health promoting behavior. This was a cross-sectional descriptive study. A total of 1,268 senior nursing students were selected using PPS (Probability Proportional to size) procedures. A self-administered questionnaire was used, involving demographic profile, spiritual health scale and health promoting profile. The findings of the study indicated that participants were all female, the average age was 20.1 years old (SD = 1.6ys) and their religion was in most cases categorized as primary religion (95.5%). The participants were distributed within four levels of the educational system (university, two-year college, four-year college and junior college). Their religion category affected their school performance, spiritual health and health promoting behavior. The results indicated that the school performance of atheists was below that of their religious counterparts. Those in the primary religion category had higher rates of good school grades. The spiritual health and the health promoting behavior of those in the primary religion category were better than those of the subjects in the secondary religion category and atheists. In the light of these results, nursing educators should pay attention to spiritual health and religious education. This might enhance opportunities for student nurses to learn about a variety of religions, which would nurture their personal spiritual health, encourage healthy lifestyles, and facilitate spiritual care for our clients.