Open Access Keynote Speech
Maria J. Santos-Martinez1
1School of Pharmacy and Pharmaceutical Sciences & School of Medicine, Trinity College Dublin, The University of Dublin, Ireland
*Corresponding author: Maria J. Santos-Martinez, School of Pharmacy and Pharmaceutical Sciences & School of Medicine, Trinity College Dublin, The University of Dublin, Ireland; Tel.: +353-18964281
E-mail: santosmm@tcd.ie
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Published: 5 May 2024; https://doi.org/10.61873/FKIQ6626
Abstract
Due to their unique physical and chemical properties, the potential application of nanomaterials in medicine is particularly attractive. Despite the many advantages that nanomaterials can offer as diagnostic and therapeutic tools, their transition from the bench to clinical practice is extremely challenging. One of the many barriers that nanomedicines may encounter is their toxicological effect. In fact, the development of novel nanomaterials / nanoparticles must proceed always in tandem with the assessment of any potential toxicological effects associated to them. Once nanomaterials reach the systemic circulation, they interact with endothelial cells, plasma proteins, and other blood components. There is no doubt that the study of nanomaterials-blood interactions is crucial to warrant the biocompatibility of nanomaterials developed for human use.
Keywords: QCM-D, nanomedicine, nanomaterials, nanotoxicology, blood platelets
Please cite as:
Santos-Martinez M.J. Applications of quartz crystal microbalance with dissipation in nanomedicine (QCM-D): a personal experience. Rev. Clin. Pharmacol. Pharmacokinet. Int. Ed. 38 (Sup2): 33-34 (2024). https://doi.org/10.61873/FKIQ6626