An Unusual Presentation of a Carcinoid Tumor of the Common Bile Duct

  • Ashif Jethava Department of Hospital Medicine, Saint Francis Hospital and Medical Center. Hartford, CT, USA
  • Visvanathan Muralidharan Department of Gastroenterology, Saint Francis Hospital and Medical Center. Hartford, CT, USA
  • Thalia Mesologites Department of Pathology, Saint Francis Hospital and Medical Center. Hartford, CT, USA
  • Elena Stoica-Mustafa Department of Pathology, Fundeni Clinical Institute. Bucharest, Romania
  • Constantin A Dasanu Department of Hematology-Oncology, Saint Francis Hospital and Medical Center. Hartford, CT, USA
Keywords: Carcinoid Tumor, Cholangiopancreatography, Endoscopic Retrograde, Common Bile Duct, Neuroendocrine Tumors, Pancreatitis

Abstract

Context Carcinoid tumors arising from the bile ducts account for only a small fraction of biliary tract cancers. Case report We report herein a 42-year-old man with a carcinoid tumor of the common bile duct. He presented with abdominal pain, bloating and dyspepsia. Clinicolaboratory and imaging studies suggested a probable obstructive common bile duct lesion. The patient underwent an endoscopic retrograde cholangiopancreatography with a stent placement in view of common bile duct decompression. Persistence of symptoms prompted a laparotomy and pancreaticoduodenectomy that revealed a well-differentiated carcinoid tumor originating in the common bile duct. Conclusion Clinician’s familiarity with the unusual sites of origin of neuroendocrine tumors and/or atypical presentation of such tumors may facilitate their early recognition and allow for a timely intervention.

Image: Nodular mass in the common bile duct lumen.

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Author Biography

Constantin A Dasanu, Department of Hematology-Oncology, Saint Francis Hospital and Medical Center. Hartford, CT, USA
Department of Hematology-Oncology, Saint Francis Hospital and Medical Center, Hartford, CT, USA

References

Chamberlain RS, Blumgart LH. Carcinoid tumors of the extra hepatic bile duct. A rare cause of malignant biliary obstruction. Cancer 1999;86:1959-1965.

Albores-Saavedra J, Batich K, Hossain S, et al. Carcinoid tumors and small-cell carcinomas of the gallbladder and extrahepatic bile ducts: a comparative study based on 221 cases from the Surveillance, Epidemiology, and End Results Program. Ann Diagn Pathol 2009;13:378-383.

Gosset A, Masson P. Tumeurs endocrines de l’appendice. Press Med 1914;25:237-239.

Davies AJ. Carcinoid tumor (argentaffinomata). Ann R Coll Engl 1959;36:560-569.

Pawlik TM, Shah S, Eckhauser FE. Carcinoid tumor of the biliary tract: treating a rare cause of bile duct obstruction. Am Surg 2003;69:98-101.

Modlin IM, Lye KD, Kidd M. A 5-decade analysis of 13,715 carcinoid tumors. Cancer 2003;97:934-959.

Barron-Rodriguez LP, Manivel JC, Mendez-Sanchez N. Carcinoid tumors of the common bile duct: evidence for its origin in metaplastic endocrine cells. Am J Gastroenterol 1991;86:1073-1076.

Hao L, Friedman AL, Mavarro VJ, et al. Carcinoid tumor of the common bile duct producing gastrin and somatostatin. J ClinGastroenterol 1996;23:63-5.

Nesi G, Lombardi A, Batignani G, et al. Well differentiated endocrine tumor of the distal common bile duct: a case study and literature review. Virchows Arch 2006;449:104-111.

Caglikulekci M, Dirlik M, Aydin O, et al. Carcinoid tumor of the common bile duct: report of a case and a review of the literature. Acta Chir Belg 2006;106:112-115.

Hubert C, Sempoux C, Berquin A, et al. Bile duct carcinoid tumors: an uncommon disease but with a good prognosis? Hepatogastroenterology 2005;52:1042-1047.

El Rassi ZS, Mohsine RM, Berger F, et al. Endocrine tumors of the extrahepatic bile ducts. Pathological and clinical aspects, surgical management and outcome. Hepatogastroenterology 2004;51:1295-1300.

Nodular mass in the common bile duct lumen
Published
2013-01-10
How to Cite
JethavaA., MuralidharanV., MesologitesT., Stoica-MustafaE., & DasanuC. (2013). An Unusual Presentation of a Carcinoid Tumor of the Common Bile Duct. JOP. Journal of the Pancreas, 14(1), 85-87. https://doi.org/10.6092/1590-8577/1232
Section
CASE REPORTS