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Nanotechnological advances of Lipid film-based biosensors for the rapid detection of biological compounds and toxicants
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posted on 2021-01-21, 06:58 authored by Georgia-Paraskevi NikoleliThe exploration of lipid membranes for the construction of nanobiosensors has recently provided the opportunity to construct devices to monitor a wide range of compounds of biological interest. Nanobiosensor miniaturization using nanotechnological tools has given novel ways to attach a wide range of “receptors” in the lipid membrane. The lipids used to construct a lipid film-based device are dipalmiloylphosphatidylcholine {DPPC} and in some cases dipalmitoylphosphatidic acid (DPPA) which is an anionic lipid and is used to increase the sensitivity of detection. Most common “receptors” used in lipid film biosensors are enzymes such as urease, cholesterol oxidase, urecase, etc, antibodies such as D-dimer antibody and artificial or natural receptors such as saxitoxin, cholera toxin, calyx [4] arene phospjoryl receptor, etc. This chapter reviews and investigates the construction of nanobiosensors based on lipid membranes that are used to monitor various toxicants. It also exploits examples of applications with an emphasis on novel devices, new nanobiosensing techniques and nanotechnology-based transduction schemes. The compounds that can be detected are insecticides, toxins, hormones, dioxins, etc.
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Lipid membrane based nanosensorsNanoyechologyGraphene and ZnO electrodesFood toxicantsEnvironmental pollutantsAnalytical Chemistry not elsewhere classifiedAnalytical SpectrometryBiochemistryBioinorganic ChemistryBiologically Active MoleculesBiomolecular Modelling and DesignCatalysis and Mechanisms of ReactionsCharacterisation of Biological MacromoleculesChemical Characterisation of Materialsf-Block ChemistryTransport Properties and Non-equilibrium ProcessesTransition Metal ChemistryTheory and Design of MaterialsTheoretical and Computational Chemistry not elsewhere classifiedSynthesis of MaterialsSupramolecular ChemistryStructural Chemistry and SpectroscopyStereochemistryStatistical Mechanics in ChemistrySolution ChemistrySeparation ScienceSolid State ChemistrySensor Technology (Chemical aspects)Reaction Kinetics and DynamicsRadiochemistryRadiation and MatterQuantum ChemistryQuality Assurance, Chemometrics, Traceability and Metrological ChemistryProteins and PeptidesPolymerisation MechanismsPhysical Organic ChemistryPhysical Chemistry of MaterialsPhysical Chemistry not elsewhere classifiedOrganometallic ChemistryOrganic Green ChemistryOrganic Chemistry not elsewhere classifiedOrganic ChemistryOrganic Chemical SynthesisOptical Properties of MaterialsNuclear ChemistryNon-metal ChemistryNatural Products ChemistryNanochemistry and Supramolecular ChemistryNMR SpectroscopyMolecular PhysicsMolecular MedicineMedicinal and Biomolecular Chemistry not elsewhere classifiedMain Group Metal ChemistryMacromolecular and Materials Chemistry not elsewhere classifiedInstrumental Methods (excl. Immunological and Bioassay Methods)Inorganic Green ChemistryInorganic Chemistry not elsewhere classifiedInorganic ChemistryIndustrial ChemistryImmunological and Bioassay MethodsGeochemistryFree Radical ChemistryForensic ChemistryFlow AnalysisEnvironmental Chemistry (incl. Atmospheric Chemistry)Environmental ChemistryElectrochemistryElectroanalytical ChemistryCrystallographyComputational ChemistryColloid and Surface ChemistryCheminformatics and Quantitative Structure-Activity RelationshipsCheminformaticsChemical Thermodynamics and EnergeticsChemical Sciences not elsewhere classified
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