13148_2020_957_MOESM5_ESM.xlsx (7.51 kB)

Additional file 5 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

dataset

posted on 2021-01-08, 04:50 authored by Monica del C. Gomez-Alonso, Anja Kretschmer, Rory Wilson, Liliane Pfeiffer, Ville Karhunen, Ilkka Seppälä, Weihua Zhang, Kirstin Mittelstraß, Simone Wahl, Pamela R. Matias-Garcia, Holger Prokisch, Sacha Horn, Thomas Meitinger, Luis R. Serrano-Garcia, Sylvain Sebert, Olli Raitakari, Marie Loh, Wolfgang Rathmann, Martina Müller-Nurasyid, Christian Herder, Michael Roden, Mikko Hurme, Marjo-Riitta Jarvelin, Mika Ala-Korpela, Jaspal S. Kooner, Annette Peters, Terho Lehtimäki, John C. Chambers, Christian Gieger, Johannes Kettunen, Melanie Waldenberger

Additional file 5: Table S4. Replication tables. Replicated associations are displayed by CpG site, CpG gene location, metabolite (metabolic measure), and metabolite type (metabolic measure type). A total of 274 significant, robust associations in the discovery cohort (KORA F4) were found.

Funding

Bundesministerium für Bildung und Forschung (DE) Munich Center of Health Sciences Deutsche Forschungsgemeinschaft (DE) Bundesministerium für Bildung und Forschung Deutsches Zentrum für Diabetes Forschung National Institute for Health Research British Heart Foundation Medical Research Council Welcome Trust NIHR Official Development Assistance European Union FP7 H2020 programs Academy of Finland Social Insurance Institution of Finland Competitive State Research Financing of the Expert Responsibility area of Kuopio, Tampere and Turku University Hospitals Diabetes Research Foundation of Finnish Diabetes Association EU Horizon 2020 European Research Council European Union’s Horizon 2020 research and innovation programme Academy of Finland (FI) Joint Programming Initiative A healthy diet for a healthy life () Consejo Nacional de Ciencia y Tecnología-México Sigrid Juséliuksen Säätiö Singapore Ministry of Health’s National Medical Research Council

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Keywords

CpG site VLDL LDL HDL Lipoprotein sizes Lipoprotein composition Fatty acids Myocardial infarction Obesity NMR

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