Additional file 1 of Add-on therapy in metformin-treated patients with type 2 diabetes at moderate cardiovascular risk: a nationwide study

Additional file 1: Table S1. ICD-10 codes used in the study. Table S2. A sensitivity analysis, in which patients were followed until a prescription was filled for any anti-diabetic therapy different from the initial treatment. Table S3. Follow-up was extended to three years instead of the initial two years in the primary analysis. Table S4. Sensitivity analyses: (A) excluding patients a high or very high cardiovascular risk, (B) only including patients at high or very high cardiovascular risk (B). Table S5. Sensitivity analyses splitting the cohort in two according to the year of inclusion (A) Patients with a date of inclusion set between 2010 January - 2013 September, (B) Patients with a date of inclusion set between 2013 October - 2017August. Table S6. A sensitivity analysis in which sulfonylurea was used as reference as opposed to DPP-4 inhibitors which was used in the primary analysis.