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CC BY-NC 4.0 · Arch Plast Surg 2012; 39(05): 457-462
DOI: 10.5999/aps.2012.39.5.457
Original Article

A Skin Fixation Method for Decreasing the Influence of Wound Contraction on Wound Healing in a Rat Model

Seong Hwan Bae
Department of Plastic and Reconstructive Surgery, Pusan National University School of Medicine, Busan, Korea
,
Yong Chan Bae
Department of Plastic and Reconstructive Surgery, Pusan National University School of Medicine, Busan, Korea
,
Su Bong Nam
Department of Plastic and Reconstructive Surgery, Pusan National University School of Medicine, Busan, Korea
,
Soo Jong Choi
Department of Plastic and Reconstructive Surgery, Pusan National University School of Medicine, Busan, Korea
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Background The elasticity of the back skin of the rat reduced the tension around wounds during the wound healing process in that region, and thus activates wound contraction. The authors proposed two skin fixation methods using readily available materials to decrease the influence of wound contraction on wound healing and designed an experiment to determine their effects.

Methods The authors made 36 skin wounds on the backs of 18 rats, and they divided them into three groups. Each group was treated with three different kinds of dressing materials, each with different skin fixing characteristics. Group A was a control group. Group B and group C were dressed by the first and the second skin fixation method. We measured the areas of the wounds post-surgically and calculated the wound area reduction rates.

Results The two skin fixation methods both reduced the effect of wound contraction compared to the control group. Each of the two methods had different outcomes in reducing wound contraction.

Conclusions The experiment demonstrated significant differences among the wound areas and the wound area reduction rates of the three groups as a result of differences in the degree of wound contraction. To obtain accurate results from wound healing experiments, appropriate skin fixation methods must be adopted.

Keywords

Wounds and injuries - Wound healing - Rats


Publication History

Received: 10 July 2012

Accepted: 22 August 2012

Article published online:
01 May 2022

© 2012. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonCommercial License, permitting unrestricted noncommercial use, distribution, and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes. (https://creativecommons.org/licenses/by-nc/4.0/)

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