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2016, vol. 50, br. 3, str. 110-114
'Collodion baby' - prikaz retkog familijarnog oblika lamelarne ihtioze
aKlinički centar Kragujevac, Klinika za pedijatriju, Srbija
bKlinički centar Kragujevac, Klinika za pedijatriju, Srbija + Univerzitet u Kragujevcu, Fakultet medicinskih nauka, Srbija

e-adresaaleksandra.simovic@yahoo.com
Ključne reči: ihtioza; lamelarna; oboljenja kože; dijagnoza; novorođenče; terapija
Sažetak
Predsmavljamo slučaj muškog novorođenčeta rođenog vaginalnim putem, u 38. gestacijskoj nedelji, iz braka nekonsangvinitetnih roditelja. U porodičnoj istoriji nema podataka o kožnim oboljenjima roditelja, ali je starija sestra takođe imala znake lamelarne ihtioze. Majka je prenatalno dobijala uobičajenu zaštitu, spontana ruptura plodovih ovojaka desila se oko dva sata pre porođaja, Apgar skor u 1. i 5. minutu iznosio je 7/7, težina 3.410 g, dužina 54 cm, a obim glave 35 cm. Nakon inicijalnog fizikalnog pregleda uočeno je postojanje tanke kolodijumske membrane, koja je prekrivala veći deo kože. Koža je bila sjajna, suva, u vidu smeđežute opne, s pukotinama u predelu vrata i na prevojima. Takođe, uočeno je izraženo izvrtanje ka spolja oba očna kapka (ectropia) i usana (eclabium) i prisustvo malih, loše modeliranih ušnih školjki. Kompletna krvna slika i biohemijske analize bili su normalni za uzrast. Serološkim analizama dokazano je povećanje titra antitela lgG klase na Rubella i Citomegalovirus. Ostali serološki testovi bili su negativni. Brisom kože izolovani su: Enterococcus species, Klebsiela-Enterobacter i Pseudomonas species. Patohistološki nalaz isečka kože pokazao je hiperkeratozu 'lamelarnog ' tipa, zadebljan granularni sloj sa izduženim epidermalnim prečkama 'zupčastog ' tipa. U gornjem dermu uočavali su se nezreli folikuli dlaka i lak stepen perivaskularnog limfocitnog infiltrata. Citogenetska analiza limfocita periferne krvi pokazala je prisustvo normalnog muškog kariotipa 46 HU.
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O članku

jezik rada: srpski
vrsta rada: prikaz slučaja
DOI: 10.5937/mckg50-13026
objavljen u SCIndeksu: 31.03.2017.

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